Supplementation and therapeutic use of vitamin D in patients with multiple sclerosis: Consensus of the Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology
Document title: Supplementation and therapeutic use of vitamin D in patients with multiple sclerosis: Consensus of the Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology
Journal: Arquivos de neuro-psiquiatria
Database: PERIÓDICA
System number: 000392514
ISSN: 0004-282X
Authors: 1
2
3
4
Institutions: 1Universidade Estadual Paulista "Julio de Mesquita Filho", Faculdade de Medicina de Botucatu, Botucatu, Sao Paulo. Brasil
2Universidade Federal de Minas Gerais, Hospital das Clinicas, Belo Horizonte, Minas Gerais. Brasil
3Universidade Federal do Rio de Janeiro, Rio de Janeiro. Brasil
4Hospital de Base do Distrito Federal, Brasilia, Distrito Federal. Brasil
Year:
Season: Feb
Volumen: 72
Number: 2
Pages: 152-156
Country: Brasil
Language: Inglés
Document type: Revisión bibliográfica
Approach: Analítico
English abstract Multiple sclerosis (MS) is an inflammatory, autoimmune, demyelinating, and degenerative central nervous system disease. Even though the etiology of MS has not yet been fully elucidated, there is evidence that genetic and environmental factors interact to cause the disease. Among the main environmental factors studied, those more likely associated with MS include certain viruses, smoking, and hypovitaminosis D. This review aimed to determine whether there is evidence to recommend the use of vitamin D as monotherapy or as adjunct therapy in patients with MS. We searched PUBMED, EMBASE, COCHRANNE, and LILACS databases for studies published until September 9 th , 2013, using the keywords “multiple sclerosis”, “vitamin D”, and “clinical trial”. There is no scientific evidence up to the production of this consensus for the use of vitamin D as monotherapy for MS in clinical practice
Portuguese abstract A esclerose múltipla (EM) é uma doença inflamatória, autoimune, desmielinizante e degenerativa do sistema nervoso central. Estudos epidemiológicos têm identificado associações de hipovitaminose D com doenças autoimunes. O principal objetivo desta revisão é responder se há evidências que indiquem o uso terapêutico de vitamina D em monoterapia para pacientes com EM. Por meio dos sites PUBMED, EMBASE, LILACS e Scielo foram realizadas buscas usando os descritores “vitamin D”, e “multiple sclerosis” até 12/09/2013. Estudos clínicos randomizados, controlados e duplo-cegos foram selecionados para avaliar a resposta terapêutica da vitamina D na EM. Não foram encontradas evidências científicas que justifiquem o uso da vitamina D em monoterapia no tratamento da EM, na prática clínica
Disciplines: Medicina
Keyword: Neurología,
Terapéutica y rehabilitación,
Inmunología,
Esclerosis múltiple,
Vitamina D,
Encefalitis autoinmune
Keyword: Medicine,
Neurology,
Therapeutics and rehabilitation,
Immunology,
Multiple sclerosis,
Vitamin D,
Autoimmune encephalitis
Full text: Texto completo (Ver HTML)