Relationship between muscle strength and motor function in Duchenne muscular dystrophy



Document title: Relationship between muscle strength and motor function in Duchenne muscular dystrophy
Journal: Arquivos de neuro-psiquiatria
Database: PERIÓDICA
System number: 000396069
ISSN: 0004-282X
Authors: 1
1
2
2
1
1
Institutions: 1Universidade de Sao Paulo, Faculdade de Medicina, Sao Paulo. Brasil
2Universidade Federal de Sao Paulo, Faculdade de Medicina, Sao Paulo. Brasil
Year:
Season: Jul
Volumen: 74
Number: 7
Pages: 530-535
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Analítico, descriptivo
English abstract Measuring muscle strength and motor function is part of Duchenne muscular dystrophy (DMD) assessment. However, the relationship between these variables is controversial. Objective To investigate the relationship between muscle strength and motor function and between these variables and age. Method Muscle strength was measured by Medical Research Council (MRC) scale and motor function, by Motor Function Measure (MFM), in 40 non-ambulatory patients. Spearman tests investigated the relationships between muscle strength, motor function and age. Results Total MRC and MFM scores were strongly related to each other (r = 0.94; p < 0.001), but not to age (r = -0.19, r = -0.31, respectively; p > 0.05). Strong and moderate relationships between partial muscle strength and motor function scores were found. Higher correlation coefficients were found between total scores and Dimensions 2 (axial/ proximal control) and 3 (distal control) of MFM. Conclusion Muscle strength and motor function are strongly correlated and seem to decrease proportionally in DMD
Portuguese abstract Investigar a relação entre força muscular, função motora e idade. Método Força muscular foi medida pela Medical Research Council (MRC), e função motora pela escala Medida da Função Motora (MFM), em 40 pacientes cadeirantes. Teste de Spearman investigou as relações entre força muscular, função motora e idade. Resultados O escore total da escala MRC e da MFM foram fortemente relacionados entre si (r = 0,94; p < 0,001), mas não com a idade (r = -0,19; r = -0,31, respectivamente; p > 0,05). Foram encontradas correlações fortes e moderadas entre os escores parciais de força muscular e função motora. As relações mais fortes ocorreram entre os escores totais, Dimensão 2 (controle axial/proximal) e 3 (controle distal) da escala MFM. Conclusão Força muscular e função motora estão fortemente correlacionadas e parecem diminuir proporcionalmente na DMD
Disciplines: Medicina
Keyword: Neurología,
Fisioterapia,
Distrofia muscular de Duchenne,
Actividad motora,
Habilidades motoras,
Fuerza muscular
Keyword: Medicine,
Neurology,
Physical therapy,
Duchenne muscular dystrophy,
Motor activity,
Motor skills,
Muscle strength
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