Prognostic value of proton magnetic resonance spectroscopy findings in near drowning patients: reversibility of the early metabolite abnormalities relates with a good outcome
Document title: Prognostic value of proton magnetic resonance spectroscopy findings in near drowning patients: reversibility of the early metabolite abnormalities relates with a good outcome
Journal: Arquivos de neuro-psiquiatria
Database: PERIÓDICA
System number: 000338493
ISSN: 0004-282X
Authors: 1
1
1
2
1
Institutions: 1Mount Sinai School of Medicine, Department of Radiology, Nueva York. Estados Unidos de América
2Universidade Federal de Pernambuco, Departamento de Neuropsiquiatria, Recife, Pernambuco. Brasil
Year:
Season: Mar
Volumen: 67
Number: 1
Pages: 55-57
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Aplicado
English abstract In two children with near drowning hypoxic encephalopathy and normal-appearing structural MRI, acute proton magnetic resonance spectroscopy (1H MRS) showed biochemical alterations that correctly indicated prognosis and helped to guide management decisions. Elevation of the lipid-lactate and glutamine-glutamate peaks, on the early (72 hour) 1H MRS, predicts a poor prognosis. Absence of lipid-lactate and glutamine-glutamate peaks on the early 1H MRS and reversibility of early mild metabolite abnormalities on follow up examination relates with good outcome
Portuguese abstract Em duas criancas vítimas de quase-afogamento com encefalopatia hipóxico-isquêmica, que apresentaram ressonância magnética por imagem normal, a espectroscopia de prótons por ressonância magnética (1H MRS) na fase aguda mostrou alterações bioquímicas que corretamente indicaram o prognóstico e ajudaram a guiar o manejo terapêutico. Elevação dos picos de lipídeo-lactato e glutamina-glutamato na 1H MRS precoce realizada com 72 horas previu um mau prognóstico. Relacionaram-se com bom prognóstico; a ausência dos picos de lipídeo-lactato e glutamina-glutamato na 1H MRS precoce, e a reversibilidade no exame de controle (3 meses) das discretas anormalidades metabólicas encontradas no primeiro exame
Disciplines: Medicina
Keyword: Diagnóstico,
Neurología,
Hipoxia,
Espectroscopia de resonancia magnética,
Ahogamiento,
Pronóstico
Keyword: Medicine,
Diagnosis,
Neurology,
Hypoxia,
Magnetic resonance spectroscopy,
Drowning,
Prognosis
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