| Journal: | Arquivos de neuro-psiquiatria |
| Database: | PERIÓDICA |
| System number: | 000405286 |
| ISSN: | 0004-282X |
| Authors: | Domingues, Renan B1 Duarte, Halina1 Rocha, Natalia P2 Teixeira, Antonio L2 |
| Institutions: | 1Universidade Federal de Minas Gerais, Programa de Pos-Graduacao em Neurociencias, Belo Horizonte, Minas Gerais. Brasil 2Universidade Federal de Minas Gerais, Faculdade de Medicina, Belo Horizonte, Minas Gerais. Brasil |
| Year: | 2015 |
| Season: | May |
| Volumen: | 73 |
| Number: | 5 |
| Pages: | 420-424 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico |
| English abstract | Neurotrophic factors (NF) are involved in pain regulation and a few studies have suggested that they may play a pathophysiological role in primary headaches. The aim of this study was to investigate NF levels in patients with tension type headache (TTH). We carried out a cross sectional study including 48 TTH patients and 48 age and gender matched controls. Beck Depression and Anxiety Inventories, and Headache Impact Test were recorded. Serum levels of NF were determined by ELISA. There were not significant differences between NF levels between TTH patients and controls. Patients with chronic and episodic TTH had not significant differences in NF levels. The presence of headache at the time of evaluation did not significantly alter the levels of NF. Depression and anxiety scores as well as headache impact did not correlate with NF levels. Our study suggest that the serum levels of NF are not altered in TTH |
| Portuguese abstract | Neurotrophic factors (NF) are involved in pain regulation and a few studies have suggested that they may play a pathophysiological role in primary headaches. The aim of this study was to investigate NF levels in patients with tension type headache (TTH). We carried out a cross sectional study including 48 TTH patients and 48 age and gender matched controls. Beck Depression and Anxiety Inventories, and Headache Impact Test were recorded. Serum levels of NF were determined by ELISA. There were not significant differences between NF levels between TTH patients and controls. Patients with chronic and episodic TTH had not significant differences in NF levels. The presence of headache at the time of evaluation did not significantly alter the levels of NF. Depression and anxiety scores as well as headache impact did not correlate with NF levels. Our study suggest that the serum levels of NF are not altered in TTH. Keywords: tension-type headache, neurotrophic factors, depression, anxiety |
| Disciplines: | Medicina |
| Keyword: | Neurología, Psiquiatría, Cefalea, Factores neurotróficos, Dolor, Depresión, Ansiedad |
| Keyword: | Medicine, Neurology, Psychiatry, Headache, Neurotrophic factors, Pain, Depression, Anxiety |
| Full text: | Texto completo (Ver PDF) |
