Motor assessment in patients with Duchenne muscular dystrophy



Document title: Motor assessment in patients with Duchenne muscular dystrophy
Journal: Arquivos de neuro-psiquiatria
Database: PERIÓDICA
System number: 000347709
ISSN: 0004-282X
Authors: 1
1
1
Institutions: 1Universidade Federal de Minas Gerais, Hospital das Clinicas, Belo Horizonte, Minas Gerais. Brasil
Year:
Season: Jun
Volumen: 70
Number: 6
Pages: 416-421
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Aplicado, analítico
English abstract OBJECTIVE: Evaluate muscle force and motor function in patients with Duchenne muscular dystrophy (DMD) in a period of six months. METHOD: Twenty children and adolescents with diagnosis of DMD were evaluated trough: measurement of the strength of the flexors and extensors of the shoulder, elbow, wrist, knee and ankle through the Medical Research Council (MRC), and application of the Motor Function Measure (MFM). The patients were evaluated twice within a six-month interval. RESULTS: Loss of muscle strength was identified in the MRC score for upper proximal members (t=-2.17, p=0.04). In the MFM, it was noted significant loss in the dimension 1 (t=-3.06, p=0.006). Moderate and strong correlations were found between the scores for muscular strength and the MFM dimensions. CONCLUSION: The MFM scale was a useful instrument in the follow up of patients with DMD. Moreover, it is a more comprehensive scale to assess patients and very good for conducting trials to evaluate treatment
Portuguese abstract OBJETIVO: Avaliar a força muscular e função motora em pacientes com distrofia muscular de Duchenne (DMD) em intervalo de seis meses. MÉTODO: Vinte crianças e adolescentes com diagnóstico de DMD foram avaliados quanto às seguintes medidas: força de flexores e extensores de ombro, cotovelo, punho, quadril, joelho e tornozelo, por meio do Medical Research Council (MRC) e aplicação da Medida da Função Motora (MFM). Os pacientes foram analisados em dois momentos, com intervalo de seis meses. RESULTADOS: Observou-se perda de força muscular identificada por meio da MRC para membros superiores proximais (t=-2,17, p=0,04). Na MFM, observou-se perda significativa na dimensão 1 (t=-3,06, p=0,006). Foram registradas correlações médias a fortes entre os escores de força muscular e as dimensões da MFM. CONCLUSÃO: A escala MFM mostrou ser um instrumento útil no acompanhamento dos pacientes com DMD. É uma escala funcional, o que a torna boa candidata para o acompanhamento de pacientes com DMD em uso de novas drogas
Disciplines: Medicina
Keyword: Diagnóstico,
Neurología,
Distrofia muscular de Duchenne,
Función motora,
Medición,
Seguimiento,
Fuerza muscular
Keyword: Medicine,
Diagnosis,
Neurology,
Duchenne muscular dystrophy,
Hyperhydrosis,
Motor function,
Measurement,
Follow up,
Muscular strength
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