Is there a consistent association between coronary heart disease and ischemic stroke caused by intracranial atherosclerosis?
Document title: Is there a consistent association between coronary heart disease and ischemic stroke caused by intracranial atherosclerosis?
Journal: Arquivos de neuro-psiquiatria
Database:
System number: 000569696
ISSN: 0004-282X
Authors: 1
1
1
6
7
Institutions: 1São Paulo University, Hospital das Clínicas, São Paulo, SP. Brasil
Year:
Season: May
Volumen: 71
Number: 5
Pages: 320-326
Country: Brasil
Language: Inglés
Portuguese abstract A doença coronária e o acidente vascular cerebral isquêmico são condições frequentemente associadas, que compartilham fatores de risco e representam grande sobrecarga à saúde mundial. Embora seja claramente reconhecida a relação entre a doença coronária sintomática ou assintomática e a aterosclerose da artéria carótida interna em sua porção extracraniana, há uma lacuna no conhecimento sobre a associação entre doença coronária e aterosclerose intracraniana, que por sua vez é associada a alto risco de recorrência de acidente vascular cerebral isquêmico e de morte por causas vasculares. é necessário avaliar se o diagnóstico precoce da doença coronária assintomática e seu tratamento agressivo podem diminuir o risco de morte por causas vasculares em pacientes com acidente vascular cerebral isquêmico ocasionado por aterosclerose intracraniana.
English abstract Coronary heart disease and ischemic stroke are frequent coexistent conditions that share risk factors and pose major burdens to global health. Even though a clear relation has been established between extracranial internal carotid artery atherosclerosis and symptomatic or asymptomatic coronary heart disease, there is a gap in knowledge about the association between intracranial atherosclerosis and coronary heart disease. Intracranial atherosclerosis is associated with high risks of stroke recurrence and vascular death. More research and clinical trials are needed to answer whether early diagnosis of asymptomatic coronary heart disease and aggressive treatment can decrease the risk of vascular death in patients with ischemic stroke caused by intracranial atherosclerosis.
Keyword: Stroke,
Coronary disease,
Intracranial arteriosclerosis,
Atherosclerosis
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