Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom



Document title: Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom
Journal: Arquivos de neuro-psiquiatria
Database: PERIÓDICA
System number: 000404476
ISSN: 0004-282X
Authors: 1
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1
2
3
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4
Institutions: 1Faculdade de Medicina de Sao Jose do Rio Preto, Hospital de Base, Sao Jose do Rio Preto, Sao Paulo. Brasil
2Universidade Federal de Sergipe, Departamento de Medicina, Aracaju, Sergipe. Brasil
3Universidade Nove de Julho, Faculdade de Medicina, Sao Paulo. Brasil
4Faculdade de Medicina de Sao Jose do Rio Preto, Departamento de Psiquiatria, Sao Jose do Rio Preto, Sao Paulo. Brasil
Year:
Season: Nov
Volumen: 73
Number: 11
Pages: 924-928
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Analítico
English abstract Objective: To present a surgical series of patients with low grade temporal gliomas causing intractable epilepsy, focusing on long-term seizure outcome. Method: A retrospective study was conducted with patients with temporal low-grade gliomas (LGG). Results: Sixty five patients with were operated in our institution. Males were more affected than females and the mean age at surgery was 32.3 ± 8.4 (9-68 years). The mean age at seizure onset was 25.7 ± 9.2 (11-66 years). Seizure outcome was classified according with Engel classification. After one year of follow up, forty two patients (64.6%) were Engel I; seventeen (26.2%) Engel II; four (6.2%) Engel III and two (3.1%) Engel IV. Statistically significant difference in seizure outcome was obtained when comparing the extension of resection. Engel I was observed in 39 patients (69.6%) with total resection and in only 3 (33.3%) patients with partial resection. Conclusion: Gross-total resection of temporal LGGs is a critically important factor in achieving seizure-freedom
Portuguese abstract Objetivo: Apresentar uma série cirúrgica de pacientes com gliomas temporais de baixo grau, causando epilepsia de difícil controle. Método: Estudo retrospectivo de pacientes com diagnóstico de glioma temporal de baixo grau temporais. Resultados: 65 pacientes com foram operados em nossa instituição. A média de idade de início das crises foi de 25,7 ± 9,2 (11-66 anos). Após um ano de acompanhamento, quarenta e dois pacientes (64,6%) estavam Engel I; dezessete (26,2%) Engel II; quatro (6,2%) Engel III e dois (3,1%) Engel IV. Houve diferença estatisticamente significativa no resultado do controle das crises quando se compara a extensão da ressecção. Engel I foi observada em 39 pacientes (69,6%) com a ressecção total e em apenas 3 (33,3%) pacientes com ressecção parcial. Conclusão: A ressecção total de glioma temporal de baixo grau temporais é um fator extremamente importante no controle das crises
Disciplines: Medicina
Keyword: Neurología,
Oncología,
Tratamiento quirúrgico,
Neoplasias,
Epilepsia,
Convulsiones
Keyword: Medicine,
Neurology,
Oncology,
Surgical treatment,
Neoplasms,
Epilepsy,
Seizures
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