Electroconvulsive therapy in Parkinson's disease



Document title: Electroconvulsive therapy in Parkinson's disease
Journal: Arquivos de neuro-psiquiatria
Database: PERIÓDICA
System number: 000386132
ISSN: 0004-282X
Authors: 1
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2
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Institutions: 1Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Laboratorio Clínico de Enfermedades Neurodegenerativas, México, Distrito Federal. México
2Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Departamento de Neuropsiquiatría, México, Distrito Federal. México
Year:
Season: Oct
Volumen: 73
Number: 10
Pages: 856-860
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Analítico, descriptivo
English abstract To analyze the effectiveness of electroconvulsive therapy for the management of depression and/or psychosis refractory to drug therapy in patients with Parkinson disease. Methods A retrospective study was carried out including patients treated with electroconvulsive therapy during the period between 2002 and 2013. A review of the literature was performed. Results A total of 27 patients were included. In regards to the neuropsychiatric diagnosis, 14 patients had major depression, 12 patients had both psychosis and depression, and only one patient had isolated psychosis. The mean number of electroconvulsive therapy sessions was 12 ± 2.8. After electroconvulsive therapy, all patients showed a statistically significant improvement in the Brief Psychiatric Rating scale (reduction of 52% points) and Hamilton Depression Rating Scale (reduction of 50% points) independent of the presence of psychosis, depression or both. Conclusion Electroconvulsive therapy is effective for the treatment of refractory neuropsychiatric symptoms in Parkinson’s disease
Portuguese abstract Analisar a eficácia da eletroconvulsoterapia para o tratamento da depressão e/ou psicoses refratária ao tratamento medicamentoso em pacientes com doença de Parkinson. Métodos Um estudo retrospectivo foi realizado com pacientes tratados com a eletroconvulsoterapia, durante o período entre 2002 e 2013. Uma revisão da literatura foi realizada. Resultados Um total de 27 pacientes foram incluídos. Em relação ao diagnóstico neuropsiquiátrico, 14 pacientes tinham depressão maior, 12 pacientes tiveram tanto psicoses e depressão, e apenas um paciente tinha isolado psicoses. O número médio de sessões de eletroconvulsoterapia foi de 12 ± 2,8. Após a eletroconvulsoterapia, todos os pacientes apresentaram uma melhora estatisticamente significativa no Brief Psychiatric Rating Scale (redução de 52% de pontos) e Hamilton Depression Rating Scale (redução de 50% de pontos), independente da presença de psicose, depressão ou ambos. Conclusão Eletroconvulsoterapia é eficaz para o tratamento de sintomas neuropsiquiátricos refractários na doença de Parkinson
Disciplines: Medicina
Keyword: Neurología,
Psiquiatría,
Terapéutica y rehabilitación,
Enfermedad de Parkinson,
Terapia electroconvulsiva,
Psicosis refractaria,
Depresión
Keyword: Medicine,
Neurology,
Psychiatry,
Therapeutics and rehabilitation,
Parkinson disease,
Electroconvulsive therapy,
Refractory psychosis,
Depression
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