| Journal: | Arquivos de neuro-psiquiatria |
| Database: | PERIÓDICA |
| System number: | 000387090 |
| ISSN: | 0004-282X |
| Authors: | McComas, Alan J1 Upton, Adrian R.M1 |
| Institutions: | 1McMaster University, Department of Medicine, Hamilton, Ontario. Canadá |
| Year: | 2015 |
| Season: | Ago |
| Volumen: | 73 |
| Number: | 8 |
| Pages: | 714-721 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | New evidence concerning the pathophysiology of migraine has come from the results of therapeutic transcranial magnetic stimulation (tTMS). The instantaneous responses to single pulses applied during the aura or headache phase, together with a number of other observations, make it unlikely that cortical spreading depression is involved in migraine. tTMS is considered to act by abolishing abnormal impulse activity in cortical pyramidal neurons and a suggestion is made as to how this activity could arise |
| Portuguese abstract | Novas evidências referentes à fisiopatologia da enxaqueca são o resultado de estimulação magnética transcraniana terapêutica (tTMS). As respostas imediatas a pulsos simples aplicados durante as fases de aura ou de cefaleia, em associação a diversas outras observações, tornam improvável a ideia de que a depressão alastrante esteja envolvida na enxaqueca. Considera-se que tTMS tenha sua ação abolindo atividade anormal de impulsos em neurônios corticais piramidais, sugerindo que esta atividade tenha um papel desencadeante |
| Disciplines: | Medicina |
| Keyword: | Neurología, Terapéutica y rehabilitación, Migraña, Fisiopatología, Depresión cortical expansiva, Estimulación magnética transcraneal |
| Keyword: | Medicine, Neurology, Therapeutics and rehabilitation, Migraine, Physiopathology, Cortical spreading depression, Transcranial magnetic stimulation |
| Full text: | Texto completo (Ver HTML) |
