Effects of nonsteroidal anti-inflammatory drug on prevalence of Helicobacter like organisms in gastric mucosa of thoroughbreds horses



Document title: Effects of nonsteroidal anti-inflammatory drug on prevalence of Helicobacter like organisms in gastric mucosa of thoroughbreds horses
Journal: Archivos venezolanos de farmacología y terapeútica
Database: PERIÓDICA
System number: 000394366
ISSN: 0798-0264
Authors: 1
1
1
Institutions: 1Universidad Central de Venezuela, Facultad de Ciencias Veterinarias, Caracas, Distrito Federal. Venezuela
Year:
Volumen: 30
Number: 3
Country: Venezuela
Language: Inglés
Document type: Artículo
Approach: Experimental, aplicado
English abstract The aim of this study was describe effects of Nonsteroidal Anti-inflammatory drug on prevalence of Helicobacter Like Organisms in gastric mucosa of Thoroughbreds horses. Were studied 54 Thoroughbred horses in the national race Track “La Rinconada” Caracas-Venezuela. All equine were treated by seven days with phenylbutazone at an intravenous dose of 4.4 mg/kg. All horses presented Equine gastric ulcer syndrome acute superficial gastritis (25/54), chronic gastritis with erosion focal (16/54), chronic gastritis with erosion focal and ulcers (14/54) in the gastric in both regions mucosa squamous region and glandular regions (fundus). Helicobacter Like Organisms infection in the stomach was confirmed by WarthinStarry (38/54). Gastric mucosa revealed numerous spiralshapedbacteria morphologically resembling Helicobacter Like Organisms in squamous regions, margo plicatus (20/38) and numerous spiral-shaped bacteria in fundic glands (18/54). In conclusion, we detected high presence of Helicobacter Like Organisms in the gastric mucosa of Thoroughbred horse’s treatment with phenylbutazone
Disciplines: Medicina veterinaria y zootecnia
Keyword: Equinos,
Medicina veterinaria,
Antiinflamatorios no esteroideos,
Helicobacter,
Mucosa gástrica,
Fenilbutazona,
Caballos,
Pura sangre
Keyword: Veterinary medicine and animal husbandry,
Equines,
Veterinary medicine,
Nonsteroidal anti-inflammatory drugs,
Helicobacter,
Gastric mucosa,
Phenylbutazone,
Horses,
Thoroughbred
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