| Journal: | Annals of hepatology |
| Database: | PERIÓDICA |
| System number: | 000409083 |
| ISSN: | 1665-2681 |
| Authors: | Gaba, Ron C1 Lakhoo, Janesh1 |
| Institutions: | 1University of Illinois, Hospital and Health Sciences System, Chicago, Illinois. Estados Unidos de América |
| Year: | 2016 |
| Volumen: | 15 |
| Number: | 2 |
| Pages: | 230-235 |
| Country: | México |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Aplicado, descriptivo |
| English abstract | There is currently no definition of post-transjugular intrahepatic portosystemic shunt (TIPS) liver failure (PTLF), which constitutes a barrier to standardization of TIPS results reporting and limits the ability to compare liver failure incidence across clinical studies. This descriptive study proposes and preliminarily tests the performance of a PTLF definition and grading system. Results. Results. Results. PTLF was defined by ≥ 3-fold bilirubin and/or ≥ 2-fold INR elevation associated with clinical outcomes of prolonged hospitalization/increase in care level (grade 1), TIPS reduction or liver transplantation (grade 2), or death (grade 3) within 30-days of TIPS. PTLF incidence was 20% (grades 1, 2, 3: 10%, 3%, 8%) among 270 TIPS cases, and the scheme identified patients at increased risk for morbidity and mortality with a statistically significant difference in clinical outcomes between PTLF and non-PTLF groups (P<0.0001). In conclusion, the PTLF definition and classification scheme put forth distributes patients into unique risk groups. PTLF grading may thus be useful for standardization of TIPS results reporting |
| Disciplines: | Medicina |
| Keyword: | Gastroenterología, Sistema cardiovascular, Derivación intrahepática portosistémica transyugular, Insuficiencia hepática, Clasificación clínica |
| Keyword: | Medicine, Cardiovascular system, Gastroenterology, Transjugular intrahepatic portosystemic shunt, Hepatic insufficiency, Clinical classification |
| Full text: | Texto completo (Ver PDF) |
