Validation of prognostic scores for clinical outcomes in cirrhotic patients with acute variceal bleeding



Document title: Validation of prognostic scores for clinical outcomes in cirrhotic patients with acute variceal bleeding
Journal: Annals of hepatology
Database: PERIÓDICA
System number: 000406036
ISSN: 1665-2681
Authors: 1
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2
3
1
4
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1
Institutions: 1Fundación Clínica Médica Sur, Unidad de Obesidad y Enfermedades Digestivas, Ciudad de México. México
2Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Endoscopia, Ciudad de México. México
3Universidad de Barcelona, Hospital Clínico, Barcelona. España
4Hospital Juárez de México, Unidad de Gastroenterología, Ciudad de México. México
Year:
Season: Nov-Dic
Volumen: 15
Number: 6
Pages: 895-901
Country: México
Language: Inglés
Document type: Artículo
Approach: Analítico, descriptivo
English abstract Rockall, Glasgow-Blatchford, and AIMS65 are useful and validated scoring systems for predicting the outcomes of patients with nonvariceal gastrointestinal bleeding. However, there are no validated evidence for using them to predict outcomes on variceal bleeding. The aim of this study was to evaluate and compare the prognostic accuracy of different nonvariceal bleeding scores with other liver-specific scoring systems in cirrhotic patients. Material and methods. Material and methods. Material and methods. A retrospective multicenter study that included 160 cirrhotic patients with acute variceal bleeding. The AUROC’s to predict in-hospital mortality, and rebleeding, were analyzed for each scoring system. Results. Results. Results. Overall in-hospital mortality occurred in 13% and in-hospital rebleeding in 12% of patients. The systems with the best AUROC value for predicting mortality were MELD (0.828; 95% CI 0.748-0.909), and AIMS65 (0.817; 95% CI 0.724-0.909). The best score systems for predicting rebleeding were Glasgow-Blatchford (0.756; 95% CI 0.640- 0.827), and Rockall (0.691; 95% CI 0.580-0.802). Conclusions. Conclusions. In Conclusions. addition to liver-specific scores, the AIMS65 score is accurate for predicting in-hospital mortality in cirrhotic patients
Disciplines: Medicina
Keyword: Diagnóstico,
Gastroenterología,
Terapéutica y rehabilitación,
Cirrosis hepática,
Sangrado digestivo,
Factores pronósticos,
Mortalidad
Keyword: Medicine,
Diagnosis,
Gastroenterology,
Therapeutics and rehabilitation,
Liver cirrhosis,
Digestive bleeding,
Prognostic factors,
Mortality
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