Papillary in situ and intramucosal adenocarcinoma of the lower third of common bile duct. A report and review of the literature



Document title: Papillary in situ and intramucosal adenocarcinoma of the lower third of common bile duct. A report and review of the literature
Journal: Annals of hepatology
Database: PERIÓDICA
System number: 000411827
ISSN: 1665-2681
Authors: 1
2
1
1
3
4
5
Institutions: 1Fundación Clínica Médica Sur, Departamento de Gastroenterología, México, Distrito Federal. México
2Fundación Clínica Médica Sur, Departamento de Patología, México, Distrito Federal. México
3Universidad La Salle, Facultad Mexicana de Medicina, México, Distrito Federal. México
4Fundación Clínica Médica Sur, Departamento de Anestesiología y Terapia Respiratoria, México, Distrito Federal. México
5Universidad Nacional Autónoma de México, Facultad de Medicina, México, Distrito Federal. México
Year:
Season: May-Jun
Volumen: 14
Number: 3
Pages: 425-429
Country: México
Language: Inglés
Document type: Artículo
Approach: Caso clínico, descriptivo
English abstract We report the case of a 37-year-old woman with no relevant medical history. She was admitted to the hospital for epigastric pain related with food intake for 4 days; the pain did not improve with symptomatic management. A laparoscopic cholecystectomy due to acute lithiasic cholecystitis was performed. However, after 4 days, postoperative painless jaundice was evident; thus, endoscopic retrograde cholangiopancreatography was performed, which revealed an amputation of intrapancreatic common bile duct, as well as secondary intra- and extrahepatic bile duct dilatation. Brushing of the distal portion of the common bile duct revealed a well-differentiated adenocarcinoma. Therefore, a Whipple procedure with pylorus preservation was performed. Pathologic diagnosis of a papillary in situ adenocarcinoma with two microscopic foci of microinvasion was established. The pathologic Tumor-Node-Metastasis (TNM) stage was pT1, pN0, pM0, R0. The patient is asymptomatic and disease-free 24 months after surgery. In general, adenocarcinomas of the extrahepatic bile ducts are uncommon and have a poor prognosis. However, symptomatic patients with early disease stages are even rarer and can be cured surgically
Disciplines: Medicina
Keyword: Cirugía,
Gastroenterología,
Oncología,
Vías biliares,
Adenocarcinoma,
Resección quirúrgica
Keyword: Medicine,
Gastroenterology,
Oncology,
Surgery,
Bile ducts,
Adenocarcinoma,
Surgical resection
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