| Journal: | Annals of hepatology |
| Database: | PERIÓDICA |
| System number: | 000406057 |
| ISSN: | 1665-2681 |
| Authors: | Routhu, Michaela1 Safka, Vaclav2 Kumar Routhu, Sunil3 Fejfar, Tomas4 Jirkovsky, Vaclav4 Krajina, Antonin5 Cermakova, Eva2 Hulek, Petr4 Hosak, Ladislav6 |
| Institutions: | 1Health Education England, Wessex. Reino Unido 2Charles University in Prague, Faculty of Medicine in Hradec Kralove, Hradec Kralove. República Checa 3Health Education West Midlands, School of Psychiatry, Birmingham. Reino Unido 4University Hospital in Hradec Kralove, Department of Internal Medicine, Hradec Kralove. República Checa 5University Hospital in Hradec Kralove, Department of Radiology, Hradec Kralove. República Checa 6University Hospital in Hradec Kralove, Department of Psychiatry, Hradec Kralove. República Checa |
| Year: | 2017 |
| Season: | Ene-Feb |
| Volumen: | 16 |
| Number: | 1 |
| Pages: | 140-148 |
| Country: | México |
| Language: | Inglés |
| Document type: | Estadística o encuesta |
| Approach: | Analítico |
| English abstract | Hepatic encephalopathy (HE) is a common complication of transjugular intrahepatic portosystemic shunting (TIPS). It is associated with a reduced quality of life and poor prognosis. The aim of this study was to compare two groups of patients who did and did not develop overt HE after TIPS. We looked for differences between these groups before TIPS. Material and methods. A study of 895 patients was conducted based on a retrospective analysis of clinical data. Data was analyzed using Fisher’s exact test, χ2, Mann Whitney test, unpaired t-test and logistic regression. After the initial analyses, we have looked at a regression models for the factors associated with development of HE after TIPS. Results. 257 (37.9%) patients developed HE after TIPS. Patients’ age, pre-TIPS portal venous pressure, serum creatinine, aspartate transaminase, albumin, presence of diabetes mellitus and etiology of portal hypertension were statistically significantly associated with the occurrence of HE after TIPS (p < 0.01). However, only the age, pre-TIPS portal venous pressure, serum creatinine, presence of diabetes mellitus and etiology of portal hypertension contributed to the regression model. Patients age, serum creatinine, presence of diabetes mellitus and portal vein pressure formed the model describing development of HE after TIPS for a subgroup of patients with refractory ascites. Conclusion. We have identified, using a substantial sample, several factors associated with the development of HE after TIPS. This could be helpful in further research |
| Disciplines: | Medicina |
| Keyword: | Gastroenterología, Neurología, Encefalopatía hepática, Hipertensión portal, Derivación intrahepática portosistémica transyugular, Complicaciones, Creatinina, Diabetes, Ascitis, Edad |
| Keyword: | Medicine, Gastroenterology, Neurology, Hepatic encephalopathy, Portal hypertension, Transjugular intrahepatic portosystemic shunt, Complications, Creatinine, Diabetes, Ascites, Age |
| Full text: | Texto completo (Ver HTML) |
