| Journal: | Annals of hepatology |
| Database: | PERIÓDICA |
| System number: | 000413419 |
| ISSN: | 1665-2681 |
| Authors: | Shi, Fuyan1 Tan, Zhijun2 An, Hongqing1 Wang, Xiaoli3 Xu, Yongyong2 Wang, Suzhen1 |
| Institutions: | 1Weifang Medical College, School of Public Health, Weifang City, Shandong. China 2Fourth Military Medical University, School of Military Preventive Medicine, Xi’an, Shaanxi. China 3Tumor Hospital, Department of Operating Room, Jinan, Shandong. China |
| Year: | 2016 |
| Season: | Ene-Feb |
| Volumen: | 15 |
| Number: | 1 |
| Pages: | 61-70 |
| Country: | México |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | To Background. compare the survival of Chinese cirrhotic patients with hepatocellular carcinoma (HCC) ≤ 4 cm who underwent radiofrequency ablation (RFA) alone or a combination of RFA with percutaneous ethanol injection (PEI). Material and methods. Material and methods. Retrospective analysis was performed for 681 cases with HCC ≤ 4 cm who were treated with RFA alone or RFA combined with PEI (RFA + PEI) between 2004 and 2011. Results. Results. As Results. a result, 180 patients in each group were selected after propensity score matching (PSM). Higher overall survival (OS) and recurrence-free survival (RFS) rates were achieved by RFA + PEI compared with RFA alone (P = 0.019 and 0.009, respectively). The 1-, 3-, and 5-year cumulative OS rates were 78.0, 44.4, and 30.1% for patients in RFA group and 88.2, 58.0, and 41.1% for patients in RFA + PEI group, respectively. Besides, the 1-, 3-, and 5-year cumulative RFS rates were 77.0, 43.8, and 29.2% in RFA group, and 87.9, 57.6, and 38.4% in RFA + PEI group, respectively. The local recurrence, complete ablation and five-year mortality showed no distinct differences between RFA and RFA + PEI groups in three subgroups classified with tumor size. Moreover, Cox regression multivariate analysis results showed that sex and treatment approach were significantly related to OS, whereas sex, status of HBsAg, local recurrence, and number of tumor nodule were related to RFS. Conclusion. Conclusion. Conclusion. Therefore, the combination of RFA and PEI yielded better OS and RFS rates than RFA alone for Chinese patients with HCC ≤ 4 cm |
| Disciplines: | Medicina |
| Keyword: | Gastroenterología, Oncología, Terapéutica y rehabilitación, Carcinoma hepatocelular, Terapia combinada, Ablación por radiofrecuencia, Alfa fetoproteína |
| Keyword: | Medicine, Gastroenterology, Oncology, Therapeutics and rehabilitation, Hepatocellular carcinoma, Combined therapy, Radiofrequency ablation, Alpha fetoprotein |
| Full text: | Texto completo (Ver PDF) |
