Hepatitis A vaccination in healthcare personnel



Document title: Hepatitis A vaccination in healthcare personnel
Journal: Annals of hepatology
Database: PERIÓDICA
System number: 000417059
ISSN: 1665-2681
Authors: 1
2
1
Institutions: 1University of Texas Medical Branch, Department of Medicine, Galveston, Texas. Estados Unidos de América
2University of Texas Medical Branch, Department of Surgery, Galveston, Texas. Estados Unidos de América
Year:
Season: May-Jun
Volumen: 11
Number: 3
Pages: 326-329
Country: México
Language: Inglés
Document type: Artículo
Approach: Analítico, descriptivo
English abstract Despite effective vaccine available, hepatitis A remains a significant cause of morbidity and mortality worldwide including acute liver failure, transplantation and death. Vaccination rates for hepatitis A in the general population are low. Rates of hepatitis A vaccination in healthcare personnel (HCP) are unknown. We studied vaccination rate to hepatitis A in a cohort of HCP at a large US academic center. Material and methods. An anonymous survey was circulated between 499 HCP at-risk of hepatitis A exposure at our Institution. Results were corrected for non-response rate and compared with the general US population using the 2007 CDC-National Immunization Survey. Rate of hepatitis A vaccination was compared with Institutional rate of vaccination for the Influenza 2009-2010 season. Results. Rate of vaccination for hepatitis A in HCP was 28.8% (response rate 41.4%; 207/499), with 58.9% having completed the full series and 24.7% being tested for post-vaccination immunity. Acceptance rate among non-vaccinated subjects was 70.7%. HCP hepatitis A vaccination rate was statistically greater than the national general population (28.8 vs. 12.1%, p ≤ 0.031). A statistically significant greater vaccination rate was found among USborn responders vs. foreign-born HCP (34.3 vs. 19.3%, p = 0.0324). Vaccination for hepatitis A was statistically inferior to that of Influenza (28.8 vs. 90%; P = 0.01). Conclusions. HCP have statistically higher vaccination rate for hepatitis A than the general population, but overall protection remains suboptimal with vaccination rate below those for mandatory vaccines. Further studies to determine whether hepatitis A vaccine is cost-effective in HCP are recommended
Disciplines: Medicina
Keyword: Gastroenterología,
Inmunología,
Prevención de infecciones,
Vacunación,
Personal de salud,
Hepatitis A
Keyword: Gastroenterology,
Immunology,
Infections prevention,
Vaccination,
Health personnel,
Hepatitis A
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