Focal nodular hyperplasia and hepatic regenerating nodules in pediatric oncology patients: how much invasive approach is necessary?
Document title: Focal nodular hyperplasia and hepatic regenerating nodules in pediatric oncology patients: how much invasive approach is necessary?
Journal: Annals of hepatology
Database: PERIÓDICA
System number: 000416667
ISSN: 1665-2681
Authors: 1
2
2
1
1
Institutions: 1Ospedale Bambino Gesu, Dipartimento di Hematologia, Roma, Lazio. Italia
2Ospedale Bambino Gesu, Dipartamento di Radiologia, Roma, Lazio. Italia
Year:
Season: Mar-Abr
Volumen: 12
Number: 2
Pages: 308-314
Country: México
Language: Inglés
Document type: Artículo
Approach: Caso clínico, analítico
English abstract Hepatic regenerating nodules (HRN) and focal nodular hyperplasia (FNH) are benign regenerating lesions of the liver that rarely occur in children. An increased incidence of these lesions is reported in children treated for cancer. Material and methods. Eight children who developed FNH and HRN after treatment for malignancies in the Oncology unit at the “Bambino Gesù” Pediatric Hospital in Rome, were retrospectively analyzed. Results. The lesions, considered in the differential diagnosis with metastatic relapse of the primitive disease, have been monitored with US or other available imaging techniques. Evolution of the lesions was observed in only 1 patient three years after the initial diagnosis of FNH. Conclusion. Serial monitoring with imaging techniques is sufficient to rule out liver metastasis and to monitor the evolution of the lesions. Surgery is suggested only in the case of complications
Disciplines: Medicina
Keyword: Gastroenterología,
Diagnóstico,
Oncología,
Hiperplasia nodular focal,
Hígado,
Niños,
Quimioterapia,
Regeneración hepática,
Seguimiento
Keyword: Gastroenterology,
Surgery,
Diagnosis,
Focal nodular hyperplasia,
Liver,
Children,
Chemotherapy,
Hepatic regeneration,
Follow up
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