| Journal: | Annals of hepatology |
| Database: | PERIÓDICA |
| System number: | 000416322 |
| ISSN: | 1665-2681 |
| Authors: | Mangano, Carmelo1 Squadrito, Giovanni2 Cacciola, Irene2 Carpentieri, Mariastella1 Foti, Giuseppe1 Raimondo, Giovanni2 |
| Institutions: | 1Ospedale Bianchi-Melacrino-Morelli , Divisione delle Malattie Infetive, Reggio Calabria, Calabria. Italia 2Ospedale Accademico di Messina, Dipartimento di Medicina Interna, Messina, Sicilia. Italia |
| Year: | 2011 |
| Season: | Ene-Mar |
| Volumen: | 10 |
| Number: | 1 |
| Pages: | 84-87 |
| Country: | México |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Caso clínico, descriptivo |
| English abstract | Hepatitis B virus (HBV) surface antigen (HBsAg) to anti-HBsAg (anti-HBs) antibody seroconversion is the best, final objective for all available chronic hepatitis B (CHB) treatments. Unfortunately, this goal is rarely obtained with the currently utilized therapeutic approaches. Here we describe the case of a CHB patient who was very successfully treated with a particular therapeutic schedule. The patient was initially treated with Lamivudine for four years. Subsequently, pegylated interferon alpha-2a was introduced for a period of one year. During this period of combined therapies, the patient showed a flare of aminotransferase values followed by complete normalization of liver biochemistry parameters and HBsAg/anti-HBs seroconversion that persisted up to 24 months after all therapies had been stopped |
| Disciplines: | Medicina |
| Keyword: | Gastroenterología, Terapéutica y rehabilitación, Hepatitis crónica, Virus de la hepatitis B, Terapia antiviral, Lamivudina, Peginterferón |
| Keyword: | Gastroenterology, Therapeutics and rehabilitation, Chronic hepatitis, Hepatitis B virus, Antiviral therapy, Lamivudine, Pegylated interferon |
| Full text: | Texto completo (Ver PDF) |
