| Journal: | Annals of hepatology |
| Database: | PERIÓDICA |
| System number: | 000418431 |
| ISSN: | 1665-2681 |
| Authors: | Shankar, Neil1 AlBasheer, Mamoun2 Marotta, Paul1 Wall, William2 McAlister, Vivian2 Chandok, Natasha1 |
| Institutions: | 1University of Western Ontario, Division of Gastroenterology, London, Ontario. Canadá 2University of Western Ontario, Division of General Surgery, London, Ontario. Canadá |
| Year: | 2011 |
| Season: | Oct-Dic |
| Volumen: | 10 |
| Number: | 4 |
| Pages: | 477-481 |
| Country: | México |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | Liver transplantation is a highly effective treatment for end-stage liver disease. However, there is debate over the practice of liver transplantation in older recipients (age ≥ 60 years) given the relative shortage of donor grafts, worse post-transplantation survival, and concern that that older patients may utilize excess resources postoperatively, thus threatening the economic feasibility of the procedure. Aim. To determine if patients ≥ 60 years of age utilize more health resources following liver transplantation compared with younger patients. Material and methods. Consecutive adult patients who underwent primary liver transplantation (n = 208) at a single center were studied over a 2.5-year period. Data were collected on clinico-demographic characteristics and resource utilization. Descriptive statistics, including means, standard deviations, or frequencies were obtained for baseline variables. Patients were stratified into 2 groups: age ≥ 60 years (n = 51) and < 60 years (n = 157). The Chi-Square Test, Mantel-Haenszel Test, 2-sample test and odds ratios were calculated to ascertain associations between age and resource utilization parameters. Regression analyses were adjusted for model for end-stage liver disease score, location before surgery, diabetes mellitus, donor age, cold ischemia time, albumin, and diagnosis of hepatitis C. Results. Recipients ≥ 60 years of age have similar lengths of hospitalization, re-operative rates, need for consultative services and readmission rates following liver transplantation, but have longer lengths of stay in the intensive care (hazard ratio 1.97, p = 0.03). Conclusion. Overall, liver transplant recipients ≥ 60 years of age utilize comparable resources following LT vs. younger recipients. Our findings have implications on cost-containment policies for liver transplantation |
| Disciplines: | Medicina |
| Keyword: | Gastroenterología, Geriatría, Ancianos, Trasplante de hígado, Recursos de salud, Costo de tratamiento |
| Keyword: | Gastroenterology, Geriatrics, Aged, Liver transplantation, Health resources, Treatment cost |
| Full text: | Texto completo (Ver PDF) |
