| Journal: | Annals of hepatology |
| Database: | PERIÓDICA |
| System number: | 000414218 |
| ISSN: | 1665-2681 |
| Authors: | O'Connor, Kate1 Walsh, Joanna C2 Schaeffer, David F1 |
| Institutions: | 1Vancouver General Hospital, Division of Anatomic Pathology, Vancouver, Columbia Británica. Canadá 2London Health Sciences Centre, Department of Pathology, London, Ontario. Canadá |
| Year: | 2014 |
| Season: | May-Jun |
| Volumen: | 13 |
| Number: | 3 |
| Pages: | 317-322 |
| Country: | México |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | Patients with hepatocellular carcinoma (HCC), the fifth most common cancer worldwide, display a highly variable clinical course, suggesting that HCC encompasses several biologically distinct subtypes. This heterogeneity has the potential to impede both treatment decisions and prognostic predictions for patients with HCC. One distinct, albeit rare, subtype of HCC is combined hepatocellular-cholangiocarcinoma (cHCC-CC), which overall carries a poorer prognosis than HCC and cholangiocarcinoma (CC) alone. This review discusses predominantly the histopathologic and pathogenetic intricacies of this tumor and highlights the need for an accurate diagnosis of this specific HCC subtype |
| Disciplines: | Medicina |
| Keyword: | Gastroenterología, Oncología, Carcinoma hepatocelular, Colangiocarcinoma, Tumores combinados, Patogénesis, Diagnóstico diferencial |
| Keyword: | Medicine, Gastroenterology, Oncology, Hepatocellular carcinoma, Cholangiocarcinoma, Combined tumors, Pathogenesis, Differential diagnosis |
| Full text: | Texto completo (Ver PDF) |
