Chronic HBV with pregnancy: Reactivation flare causing fulminant hepatic failure



Document title: Chronic HBV with pregnancy: Reactivation flare causing fulminant hepatic failure
Journal: Annals of hepatology
Database: PERIÓDICA
System number: 000417037
ISSN: 1665-2681
Authors: 1
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1
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Institutions: 1INTEGRIS Baptist Medical Center, Nazih Zuhdi Transplant Institute, Oklahoma City, Oklahoma. Estados Unidos de América
Year:
Season: Abr-Jun
Volumen: 10
Number: 2
Pages: 233-236
Country: México
Language: Inglés
Document type: Artículo
Approach: Analítico, descriptivo
English abstract Chronic HBV infection is a dynamic state of interaction between HBV, hepatocytes, and the immune system of the host. A series of reactivation flares and remissions may occur due to multiple causes. Among them, spontaneous reactivation and immunosuppressive drugs including steroids or cancer chemotherapy are well known. This is due to immune-mediated destruction of HBV-expressing cells following withdrawal of immunosuppressive effect. Few cases have been reported in females during postpartum period. We report a case of fulminant hepatic failure during pregnancy in a previously unrecognized hepatitis B positive female requiring emergent liver transplantation
Disciplines: Medicina
Keyword: Gastroenterología,
Ginecología y obstetricia,
Embarazo,
Virus de la hepatitis B,
Reactivación viral,
Falla hepática fulminante,
Trasplante de hígado,
Inmunosupresión
Keyword: Gastroenterology,
Gynecology and obstetrics,
Pregnancy,
Hepatitis B virus,
Viral reactivation,
Fulminant liver failure,
Liver transplantation,
Immunosuppression
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