The influence of non-steroidal anti-inflammatory drugs and paracetamol used for pain control of orthodontic tooth movement: a systematic review



Document title: The influence of non-steroidal anti-inflammatory drugs and paracetamol used for pain control of orthodontic tooth movement: a systematic review
Journal: Anais da Academia Brasileira de Ciencias
Database: PERIÓDICA
System number: 000417634
ISSN: 0001-3765
Authors: 1
2
1
3
2
4
2
5
Institutions: 1Universidade do Sagrado Coracao, Centro de Ciencias da Saude, Bauru, Sao Paulo. Brasil
2Universidade Federal de Sergipe, Departamento de Odontologia, Lagarto, Sergipe. Brasil
3Universidade Federal do Parana, Departamento de Estomatologia, Curitiba, Parana. Brasil
4Universidade Federal de Sergipe, Departamento de Fisiologia, Sao Cristovao, Sergipe. Brasil
5Universidade Estadual Paulista "Julio de Mesquita Filho", Instituto de Ciencia e Tecnologia, Sao Jose dos Campos, Sao Paulo. Brasil
Year:
Season: Dic
Volumen: 89
Number: 4
Pages: 2851-2864
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Experimental, aplicado
English abstract The present study aimed to perform a systematic literature review to determine if there is a non-steroidal anti-inflammatory drug (NSAID) that interferes less within tooth movement. This research was performed according to the PRISMA statement. Articles were searched in eight electronic databases (PubMed, Scopus, Embase, Web of Science, LILACS, SciELO, Google Scholar, and Open Grey). Only experimental studies on male Wistar rats were selected, which included experiments related to the influence of NSAIDs on orthodontic movement. Studies in animals with pathological conditions, literature review articles, letters to the editor and/or editorials, case reports, abstracts, books, and book chapters were excluded. Each of the steps of this systematic literature review was performed by two examiners independently. Results: the total sample consisted of 505 articles, from which 6 studies were eligible after a qualitative analysis. From the drugs assessed, paracetamol was unanimous for not interfering within orthodontic movement when compared to the control group. However, drugs such as aspirin, ibuprofen, sodium diclofenac, and selective cyclooxygenase-2 inhibitors caused a reduction in tooth movement when compared to the control group. Conclusion: paracetamol could be considered the drug of choice for pain relief because it interferes less within tooth movement
Disciplines: Medicina
Keyword: Odontología,
Farmacología,
Ortodoncia,
Movimiento dentario,
Dolor,
Analgésicos,
Antiinflamatorios no esteroideos
Keyword: Dentistry,
Pharmacology,
Orthodontics,
Tooth movement,
Pain,
Analgesics,
Non steroidal antinflammatory drugs
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