| Journal: | Anais da Academia Brasileira de Ciencias |
| Database: | PERIÓDICA |
| System number: | 000408886 |
| ISSN: | 0001-3765 |
| Authors: | Xu, Aifei1 Fan, Zhong1 Chen, Zhiyan1 Zhou, Yun1 Liu, Shaohua1 Huang, Shijie1 Xu, Xuequin1 Long, Congyun2 Wang, Weigang1 Zhu, Jing1 Li, Xiaolan1 Xu, Chunping3 |
| Institutions: | 1China Tobacco Guangxi Industrial Co. Ltd., Technical Center, Nanning, Guanxi. China 2China Tobacco Guangxi Industrial Co. Ltd., Liuzhou Cigarette Factory, Liuzhou, Guangxi. China 3Zhengzhou University of Light Industry, College of Food and Biological Engineering, Zhengzhou, Henan. China |
| Year: | 2017 |
| Season: | May |
| Volumen: | 89 |
| Pages: | 383-390 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Nota breve o noticia |
| Approach: | Analítico, descriptivo |
| English abstract | A simple and sensitive method for simultaneous determination of furan and vinyl acetate (VA) in vapor phase of mainstream cigarette smoke with cold trap and gas chromatography-mass spectrometry (GC-MS) was developed. A Cambridge filter pad (CFP) was placed in front of the impingers of smoking machine to remove the particle phase from cigarette smoke. Furan and VA in vapor phase of mainstream cigarette smoke were collected in two impingers connected in series by filled with methanol at –78°C. The solutions were added with deuterium-labeled furan- d 4 and VA- d 6 as internal standards and analyzed by GC-MS. The results showed that the calibration curves for furan and VA were linear (r 2 > 0.9995) over the studied concentration range. The intra- and inter-day precision values for furan and VA were <7.07% and <9.62%, respectively. The extraction recoveries of furan and VA were in the range of 94.5-97.7% and 92.3-94.9%, respectively. Moreover, the limits of detection for furan and VA were 0.028 μg mL -1 and 1.3 ng mL -1 , respectively. The validated method has been successfully applied to determine the emissions of furan and VA in the vapor phase of mainstream cigarette smoke under International Organization for Standardization (ISO) and Canadian Intense (CI) smoking regimen |
| Disciplines: | Química, Medicina |
| Keyword: | Química analítica, Salud pública, Toxicología, Humo, Cigarrillos, Furano, Acetato de vinilo, Cromatografía de gases, Espectrometría de masas |
| Keyword: | Chemistry, Medicine, Analytical chemistry, Public health, Toxicology, Smoke, Cigarettes, Furan, Vinyl acetate, Mass spectrometry, Gas chromatography |
| Full text: | Texto completo (Ver PDF) |
