Journal: | Anais da Academia Brasileira de Ciencias |
Database: | PERIÓDICA |
System number: | 000400416 |
ISSN: | 0001-3765 |
Authors: | Alves, Vanessa G1 Souza, Alan G1 Chiavelli, Lucas U.R1 Ruiz, Ana L.T.G2 Pomini, Armando M1 Silva, Cleuza C1 |
Institutions: | 1Universidade Estadual de Maringa, Departamento de Quimica, Maringa, Parana. Brasil 2Universidade Estadual de Campinas, Instituto de Quimica, Paulinia, Sao Paulo. Brasil |
Year: | 2016 |
Season: | Sep |
Volumen: | 88 |
Number: | 3 |
Pages: | 1201-1210 |
Country: | Brasil |
Language: | Inglés |
Document type: | Artículo |
Approach: | Experimental, aplicado |
English abstract | The cultivation of sugarcane hybrids (X Saccharum officinarum L.) is an important revenue source for the Brazilian economy. Herein it is reported the evaluation of the cytotoxic activity of mid-polarity sugarcane extracts against human cancer cell lines, as well as the isolation of steroids sitosterol, stigmasterol and campesterol, phenolic acids p-hydroxybenzoic, p-hydroxycinnamic, vanillic and ferulic acid, terpenoids α-tocopherol and β-carotene and a novel substance in sugarcane, the flavonoid aglycone tricin (5,7,4-trihydroxy-3,5-dimethoxyflavone). The presence of large amounts of phenolic acids and the flavonoid tricin may explain the cytostatic activity observed for the mid-polarity crude extract and filtrates |
Disciplines: | Química, Medicina |
Keyword: | Fitoquímica, Farmacología, Oncología, Caña de azúcar, Compuestos fenólicos, Anticancerígenos, Saccharum officinarum |
Keyword: | Chemistry, Medicine, Phytochemistry, Oncology, Pharmacology, Sugar cane, Phenolic compounds, Anticarcinogenic agents, Saccharum officinarum |
Full text: | Texto completo (Ver HTML) |