Phenolic compounds and anticancer activity of commercial sugarcane cultivated in Brazil



Document title: Phenolic compounds and anticancer activity of commercial sugarcane cultivated in Brazil
Journal: Anais da Academia Brasileira de Ciencias
Database: PERIÓDICA
System number: 000400416
ISSN: 0001-3765
Authors: 1
1
1
2
1
1
Institutions: 1Universidade Estadual de Maringa, Departamento de Quimica, Maringa, Parana. Brasil
2Universidade Estadual de Campinas, Instituto de Quimica, Paulinia, Sao Paulo. Brasil
Year:
Season: Sep
Volumen: 88
Number: 3
Pages: 1201-1210
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Experimental, aplicado
English abstract The cultivation of sugarcane hybrids (X Saccharum officinarum L.) is an important revenue source for the Brazilian economy. Herein it is reported the evaluation of the cytotoxic activity of mid-polarity sugarcane extracts against human cancer cell lines, as well as the isolation of steroids sitosterol, stigmasterol and campesterol, phenolic acids p-hydroxybenzoic, p-hydroxycinnamic, vanillic and ferulic acid, terpenoids α-tocopherol and β-carotene and a novel substance in sugarcane, the flavonoid aglycone tricin (5,7,4-trihydroxy-3,5-dimethoxyflavone). The presence of large amounts of phenolic acids and the flavonoid tricin may explain the cytostatic activity observed for the mid-polarity crude extract and filtrates
Disciplines: Química,
Medicina
Keyword: Fitoquímica,
Farmacología,
Oncología,
Caña de azúcar,
Compuestos fenólicos,
Anticancerígenos,
Saccharum officinarum
Keyword: Chemistry,
Medicine,
Phytochemistry,
Oncology,
Pharmacology,
Sugar cane,
Phenolic compounds,
Anticarcinogenic agents,
Saccharum officinarum
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