| Journal: | Anais da Academia Brasileira de Ciencias |
| Database: | PERIÓDICA |
| System number: | 000400483 |
| ISSN: | 0001-3765 |
| Authors: | Gushiken, Carolina Y1 Medeiros, Liliane B1 Correia, Bruna P2 Souza, Joyce M1 Moris, Daniela V1 Pereira, Valeria C1 Rodrigues, Marcus V.P1 Giuffrida, Rogerio3 |
| Institutions: | 1Universidade do Oeste Paulista, Faculdade de Biomedicina, Presidente Prudente, Sao Paulo. Brasil 2Universidade do Oeste Paulista, Faculdade de Medicina de Presidente Prudente, Presidente Prudente, Sao Paulo. Brasil 3Universidade do Oeste Paulista, Programa de Pos-Graducao em Meio Ambiente e Desenvolvimento Regional, Presidente Prudente, Sao Paulo. Brasil |
| Year: | 2016 |
| Season: | Sep |
| Volumen: | 88 |
| Number: | 3 |
| Pages: | 1501-1510 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | Staphylococcus aureus can cause a variety of infections due to its high transmissibility, high pathogenic potential and resistance to multiple drugs, factors that contribute to the relevance of infections in healthcare services. The aim of this study was to document phenotypic and genotypic resistance factors of Staphylococcus aureus strains, isolated from nasal mucosa of medical students. A nasal swab was collected from the nares (nostrils) of 222 medical students. After collection, the samples were submitted to isolation and identification procedures. From 204 valid samples, 20.6% (42 samples) were positive for S. aureus. For the assessment of phenotypic resistance by disk-diffusion technique, from 42 samples, 95.2% showed resistance to erythromycin, 42.8% to clindamycin, 16.6% to cephoxitin and 9.5% to oxacillin. The D test showed that 26.2% of samples were resistant to macrolides, lincosamides and streptogramin B. A PCR assay allowed for the evaluation of a genotypic resistance profile, in which 16.6% of the samples were positive for the mecA gene, 35.7% positive for the ermC gene or ermA gene and 28.5% were positive for both genes. These results demonstrate that medical students can enter the healthcare service previously colonized by multidrug resistant strains and become potential spreaders in the hospital environment |
| Disciplines: | Medicina |
| Keyword: | Microbiología, Bacterias, Resistencia a fármacos, Patogenicidad, Portadores nasales, Staphylococcus aureus |
| Keyword: | Medicine, Microbiology, Bacteria, Drug resistance, Pathogenicity, Nasal carriers, Staphylococcus aureus |
| Full text: | Texto completo (Ver HTML) |
