Nanoencapsulated Melaleuca alternifolia essential oil exerts anesthetic effects in the brachyuran crab using Neohelice granulate



Document title: Nanoencapsulated Melaleuca alternifolia essential oil exerts anesthetic effects in the brachyuran crab using Neohelice granulate
Journal: Anais da Academia Brasileira de Ciencias
Database: PERIÓDICA
System number: 000424378
ISSN: 0001-3765
Authors: 1
2
3
4
2
2
3
5
6
7
1
Institutions: 1Universidade Federal de Santa Maria, Departamento de Fisiologia e Farmacologia, Santa Maria, Rio Grande do Sul. Brasil
2Universidade Federal do Rio Grande, Instituto de Ciencias Biologicas, Rio Grande, Rio Grande do Sul. Brasil
3Universidade Federal de Santa Maria, Departamento de Microbiologia e Parasitologia, Santa Maria, Rio Grande do Sul. Brasil
4Universidade Federal do Rio Grande, Instituto de Oceanografia, Rio Grande, Rio Grande do Sul. Brasil
5Centro Universitario Franciscano, Laboratorio de Nanotecnologia, Santa Maria, Rio Grande do Sul. Brasil
6Universidade Federal de Santa Maria, Departamento de Farmácia Industrial, Santa Maria, Rio Grande do Sul. Brasil
7Centro de Educacao Superior Norte do Rio Grande do Sul, Campus Frederico Westphalen, Frederico Westphalen, Rio Grande do Sul. Brasil
Year:
Season: Sep
Volumen: 90
Number: 3
Pages: 2855-2864
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Experimental, aplicado
English abstract The aim of this study was to evaluate the efficacy and safety of several anesthetics in the brachyuran crab Neohelice granulata, an emergent experimental model. The essential oils (EOs) of Lippia alba, Aloysia tryphilla, and Melaleuca alternifolia (tea tree oil; TTO), the isolated compounds eugenol, menthol, terpinen-4-ol, and the nanoencapsulated form of TTO, were administered in one or more of the following ways: added to the water (immersion), through an arthrodial membrane (injected), or by oral gavage. Unexpectedly, most EOs did not produce an anesthetic effect after immersion. Only TTO and eugenol induced anesthesia by immersion, with very long induction and recovery times compared to anesthesia of other crustaceans. However, a good anesthetic effect was observed with the injection of terpinen-4-ol and nanoencapsulated TTO in N. granulata; both demonstrated ideal induction and recovery times. These substances appear to be promising anesthetic alternatives for crustaceans
Disciplines: Biología
Keyword: Crustáceos,
Fisiología animal,
Fitoquímica,
Cangrejos,
Anestésicos,
Eugenol,
Terpineol,
Melaleuca alternifolia,
Myrtaceae,
Neohelice granulate
Keyword: Crustaceans,
Animal physiology,
Phytochemistry,
Crabs,
Anesthetics,
Eugenol,
Terpineol,
Melaleuca alternifolia,
Myrtaceae,
Neohelice granulate
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