| Journal: | Anais da Academia Brasileira de Ciencias |
| Database: | PERIÓDICA |
| System number: | 000436196 |
| ISSN: | 0001-3765 |
| Authors: | Lacerda Santos, Rogério1 Lima, Antonia Bárbara L2 Penha, Elizandra S. da2 Santos, Antonielson dos3 Carvalho, Fabíola G1 Pithon, Matheus M4 Dantas, Antonio Flávio M3 |
| Institutions: | 1Universidade Federal de Juiz de Fora, Instituto de Ciencias da Vida, Governador Valadares, Minas Gerais. Brasil 2Universidade Federal de Campina Grande, Faculdade de Odontologia, Patos, Paraiba. Brasil 3Universidade Federal de Campina Grande, Faculdade de Medicina Veterinaria, Patos, Paraiba. Brasil 4Universidade Estadual do Sudoeste da Bahia, Faculdade de Odontologia, Jequie, Bahia. Brasil |
| Year: | 2020 |
| Volumen: | 92 |
| Number: | 1 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | The focus of this study was to test the hypothesis that there would be no difference between the biocompatibility of silicon dioxide nanofilms used as antimicrobial agents. Sixty male Wistar rats were divided into 4 groups (n=15): Group C (Control,Polyethylene), Group AR (Acrylic Resin), Group NP (Acrylic Resin coated with NP-Liquid), Group BG (Acrylic Resin coated with Bacterlon).the animals were sacrificed with 7,15 and 30 days and tissues analyzed as regardsthe events of inflammatory infiltrate, edema, necrosis, granulation tissue, mutinucleated giant cells, fibroblasts and collagen. Kruskal-Wallis and Dunn tests was used (P<0.05). Intense inflammatory infiltrate was shown mainly in Groups BG and AR, with significant difference from Control Group inthe time interval of 7days (P=0.004). Necrosis demonstrated significant difference between Group BG and Control Group (P<0.05) inthe time intervals of 7 days. For collagen fibers,there was significant difference betweenthe Control Group and Groups AR and BG inthe time interval of 7 days (P=0.006), and between BG and Control Groups inthe time intervals of 15 days (P=0.010).the hypothesis was rejected. Bacterlon demonstratedthe lowest level, and NP-Liquid Glassthe highest level of tissue compatibility, and best cell repair.the coating with NP-Liquid Glass was demonstrated to be highly promising for clinical use |
| Disciplines: | Medicina |
| Keyword: | Odontología, Biomateriales, Dióxido de silicio, Inflamación, Actividad antimicrobiana |
| Keyword: | Dentistry, Biomaterials, Silicon dioxide, Inflammation, Biocompatibility, Antimicrobial activity |
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