| Journal: | Anais da Academia Brasileira de Ciencias |
| Database: | PERIÓDICA |
| System number: | 000418068 |
| ISSN: | 0001-3765 |
| Authors: | Corvino, Silvana B1 Damasceno, Debora C1 Sinzato, Yuri K1 Netto, Aline O1 Macedo, Nathalia C.D1 Zambrano, Elena2 Volpato, Gustavo T1 |
| Institutions: | 1Universidade Estadual Paulista "Julio de Mesquita Filho", Faculdade de Medicina de Botucatu, Botucatu, Sao Paulo. Brasil 2Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Biología Reproductiva, Ciudad de México. México |
| Year: | 2017 |
| Season: | Mar |
| Volumen: | 89 |
| Number: | 1 |
| Pages: | 223-230 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | The aim of this study was to compare two models of swimming applied to pregnant rats born small for pregnancy age (SPA). Diabetes was chemically induced in adult female rats to develop an inadequate intrauterine environment, leading to birth of a SPA offspring. In adulthood, the female SPA rats were mated and submitted to different swimming programs. The exercise program 1 (Ex1) consisted of swimming for 15 minutes, followed by 15 minutes of rest and another 15 minutes of swimming, 3 days a week before and during pregnancy. Another program (Ex2) was applied during 60 minutes uninterrupted a day, 6 days/week during pregnancy. The pregnant rats presented no interference on body weight and glycemia. The rats submitted to Ex2 model showed decreased insulin and blood glucose levels by oral glucose tolerance test, and reduction in area under curve values. The offspring from dams submitted to both exercise protocols presented an increased rate of newborns SPA. However, the offspring from Ex2 dams showed percentage twice higher of newborns SPA than Ex1 offspring. Our data suggests that continuous exercise of 60 min/day ameliorated the enhanced peripheral insulin sensitivity in growth-restricted females. However, this protocol employed at pregnancy leads to intrauterine growth restriction |
| Disciplines: | Biología, Medicina |
| Keyword: | Medicina experimental, Diabetes, Ratas, Ejercicio físico |
| Keyword: | Experimental medicine, Diabetes, Rats, Physical exercise |
| Full text: | Texto completo (Ver HTML) |
