Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity
Document title: Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity
Journal: Anais da Academia Brasileira de Ciencias
Database: PERIÓDICA
System number: 000366291
ISSN: 0001-3765
Authors: 1
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Institutions: 1Universidade Federal do Para, Faculdade de Quimica, Belem, Para. Brasil
2Universidade Federal do Amazonas, Departamento de Quimica, Manaus, Amazonas. Brasil
Year:
Season: Dic
Volumen: 85
Number: 4
Pages: 1247-1252
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Experimental, aplicado
English abstract The present work reports the isolation of five compounds from Aspergillus sp EJC08 isolated as endophytic from Bauhinia guianensis, a tipical plant of the Amazon. The compounds ergosterol (1), ergosterol peroxide (2), mevalolactone (3), monomethylsulochrin (4) and trypacidin A (5) were isolated by chromatographic procedures and identified by spectral methods of 1D and 2D NMR and MS. Compounds 3, 4 and 5 were tested against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus and showed good activity
Portuguese abstract Neste trabalho estamos reportando o isolamento de cinco compostos de Aspergillus sp EJC08 isolado como endofítico de Bauhinia guianensis uma planta típica da Amazônia. Os compostos ergosterol (1), peróxido de ergosterol (2), mevalolactona (3), monometilsulocrina (4) e tripacidina A (5) foram isolados através de procedimentos cromatográficos e identificados por métodos espectrais de RMN 1D e 2D e EM. Os compostos 3, 4 e 5 foram testados contra Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis e Staphylococcus aureus e mostraram boa atividade
Disciplines: Biología,
Química
Keyword: Hongos,
Fitoquímica,
Hongos endofíticos,
Composición química,
Actividad antibacteriana,
Aspergillus,
Bauhinia guianensis
Keyword: Biology,
Chemistry,
Fungi,
Phytochemistry,
Endophytic fungi,
Chemical composition,
Antibacterial activity,
Aspergillus,
Bauhinia guianensis
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