Cardiac glycosides and COVID-19: would it be a promising therapeutic approach?
Título del documento: Cardiac glycosides and COVID-19: would it be a promising therapeutic approach?
Revista: Anais da Academia Brasileira de Ciencias
Base de datos: PERIÓDICA
Número de sistema: 000435849
ISSN: 0001-3765
Autores: 1
1
2
Instituciones: 1Sotiria Chest Diseases Hospital, Department of Cardiology, Atenas. Grecia
2Sotiria Chest Diseases Hospital, Department of Clinical Biochemistry, Atenas. Grecia
Año:
Volumen: 92
Número: 4
País: Brasil
Idioma: Inglés
Tipo de documento: Correspondencia
Enfoque: Analítico, prospectivo
Resumen en inglés Cardiac glycosides have been found to have an anti-viral effect. This was noted in the past during various epidemics including MERS and SARS. It is due to their inhibitory effect on the Na, K-ATPase membrane pump. Furthermore, they exhibit anti-inflammatory properties. These preclinical observations may prove useful in further clinical utility of these well-known compounds in the current COVID-19 pandemic
Disciplinas: Medicina
Palabras clave: Virus,
Farmacología,
COVID-19,
Glucósidos cardiacos,
Actividad antiviral
Keyword: Virus,
Pharmacology,
Antiviral activity,
Cardiac glycosides,
COVID-19
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