| Journal: | Anais da Academia Brasileira de Ciencias |
| Database: | PERIÓDICA |
| System number: | 000435849 |
| ISSN: | 0001-3765 |
| Authors: | Siniorakis, Eftychios1 Arvanitakis, Spyridon1 Elkouris, Maximilianos2 |
| Institutions: | 1Sotiria Chest Diseases Hospital, Department of Cardiology, Atenas. Grecia 2Sotiria Chest Diseases Hospital, Department of Clinical Biochemistry, Atenas. Grecia |
| Year: | 2020 |
| Volumen: | 92 |
| Number: | 4 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Correspondencia |
| Approach: | Analítico, prospectivo |
| English abstract | Cardiac glycosides have been found to have an anti-viral effect. This was noted in the past during various epidemics including MERS and SARS. It is due to their inhibitory effect on the Na, K-ATPase membrane pump. Furthermore, they exhibit anti-inflammatory properties. These preclinical observations may prove useful in further clinical utility of these well-known compounds in the current COVID-19 pandemic |
| Disciplines: | Medicina |
| Keyword: | Virus, Farmacología, COVID-19, Glucósidos cardiacos, Actividad antiviral |
| Keyword: | Virus, Pharmacology, Antiviral activity, Cardiac glycosides, COVID-19 |
| Full text: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
