Anthelmintic acetogenin from Annona squamosa L. Seeds



Document title: Anthelmintic acetogenin from Annona squamosa L. Seeds
Journal: Anais da Academia Brasileira de Ciencias
Database: PERIÓDICA
System number: 000364862
ISSN: 0001-3765
Authors: 1
1
2
1
2
3
Institutions: 1Universidade Estadual do Ceara, Laboratorio de Doencas Parasitarias, Fortaleza, Ceara. Brasil
2Universidade Estadual do Ceara, Fortaleza, Ceara. Brasil
3Universidade Estadual do Norte Fluminense Darcy Ribeiro, Setor de Quimica de Produtos Naturais, Campos dos Goytacazes, Rio de Janeiro. Brasil
Year:
Season: Jun
Volumen: 80
Number: 2
Pages: 271-277
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Experimental, analítico
English abstract Annona squamosa seeds extracts showed anthelmintic activity against Haemonchus contortus, the main nematode of sheep and goat in Northeastern Brazil. A compound 1 was isolated from ethyl acetate extract and inhibited the egg hatching of H. contortus at 25 mg ml-1. The structure of 1 was determined as a C37 trihydroxy adjacent bistetrahydrofuran acetogenin based on spectroscopic analysis
Portuguese abstract Annona squamosa seeds extracts showed anthelmintic activity against Haemonchus contortus, the main nematode of sheep and goat in Northeastern Brazil. A compound 1 was isolated from ethyl acetate extract and inhibited the egg hatching of H. contortus at 25 mg ml-1. The structure of 1 was determined as a C37 trihydroxy adjacent bistetrahydrofuran acetogenin based on spectroscopic analysis
Disciplines: Química,
Biología
Keyword: Química farmacéutica,
Angiospermas,
Helmintos,
Annonaceae,
Annona squamosa,
Plantas medicinales,
Semillas,
Acetogeninas,
Nemátodos,
Haemonchus contortus,
Antihelmínticos,
Fitoterapia
Keyword: Chemistry,
Biology,
Medicinal chemistry,
Angiosperms,
Helminths,
Haemonchus contortus,
Annonaceae,
Annona squamosa,
Seeds,
Acetogenins,
Nematodes,
Anthelmintics,
Phytotherapy
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