| Journal: | Anais brasileiros de dermatologia |
| Database: | PERIÓDICA |
| System number: | 000410448 |
| ISSN: | 0365-0596 |
| Authors: | Almeida-Junior, Hiram Larangeira de1 Almeida, Mariana Geber de2 Jorge, Valwria Magalhaes2 Abreu, Luciana Boff de3 |
| Institutions: | 1Universidade Federal de Pelotas, Departamento de Dermatologia, Pelotas, Rio Grande do Sul. Brasil 2Universidade Catolica de Pelotas, Programa de Pos-Graduacao em Saude e Comportamento, Pelotas, Rio Grande do Sul. Brasil 3Pontificia Universidade Catolica do Rio Grande do Sul, Servico de Dermatologia, Porto Alegre, Rio Grande do Sul. Brasil |
| Year: | 2017 |
| Season: | Jul-Ago |
| Volumen: | 92 |
| Number: | 4 |
| Pages: | 528-531 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Caso clínico, descriptivo |
| English abstract | We report the ultrastructural findings in a case of a 72-year-old black woman with confluent yellowish papules in the cervical region. She had no comorbidities. Ophthalmological examination, electrocardiogram, and echocardiogram were normal. Hematoxylin-eosin staining of the affected skin showed strong alterations in the mid-dermis with irregular clumps of eosinophilic material and loss of the normal parallel arrangement of collagen bundles. Orcein staining revealed that the elastic fibers lost their normal linear configuration, showing clump fragmentation, sometimes forming square structures. Transmission electron microscopy showed aberrant elastic fibers with an irregular outline and heterogenic inner structures. We also observed small elastic fibers. Collagen fibers showed a normal structure with irregular distribution. Scanning electron microscopy revealed important disorganization of collagen fibers and small stone-like deposits measuring around 5 µm associated with bigger structures ranging from 10-16 µm. Higher magnification revealed that these small stone-like structures were sometimes polyhedral-shaped or squared |
| Disciplines: | Medicina |
| Keyword: | Dermatología, Pseudoxantoma elástico, Histopatología, Microscopía electrónica |
| Keyword: | Medicine, Dermatology, Pseudoxanthoma elasticum, Histopathology, Electron microscopy |
| Full text: | Texto completo (Ver HTML) |
