| Journal: | Anais brasileiros de dermatologia |
| Database: | |
| System number: | 000557878 |
| ISSN: | 0365-0596 |
| Authors: | Moricz, Claudia Zavaloni Melotti de1 Sanches Jr., José Antonio1 |
| Institutions: | 1Universidade de São Paulo, Faculdade de Medicina, São Paulo, SP. Brasil |
| Year: | 2005 |
| Season: | Sep-Oct |
| Volumen: | 80 |
| Number: | 5 |
| Pages: | 461-471 |
| Country: | Brasil |
| Language: | Portugués |
| Portuguese abstract | Os linfomas cutâneos primários de células B pertencem ao grupo das neoplasias malignas originadas de linfócitos B, do tipo não-Hodgkin. A rotina diagnóstica nos processos linfoproliferativos de células B é realizada pela biópsia da pele lesada para a análise histopatológica, imuno-histoquímica e pesquisa do rearranjo gênico. A classificação dos linfomas cutâneos primários vem sendo discutida nos últimos anos; as usualmente utilizadas são as propostas pela World Health Organization - WHO e pela European Organization for Research and Treatment of Cancer - EORTC. A recente classificação consensual proposta por WHO-EORTC deverá substituí-las. Entretanto, apesar dos recentes progressos, ainda existem controvérsias e dificuldades quanto à classificação, ao diagnóstico e ao tratamento dos linfomas cutâneos primários de células B. |
| English abstract | Primary cutaneous B-cell lymphomas comprise a group of malignant neoplasms originated from the B-cell lymphoid lineage, of the non-Hodgkin type. The diagnostic routine of cutaneous B-cell lymphoproliferative processes consists of a skin biopsy for histopathological, immunohistochemical and gene rearrangement analysis. The classification of primary cutaneous lymphomas is still controversial. The currently most usual classifications are those proposed by the World Health Organization (WHO) and by the European Organization for Research and Treatment of Cancer (EORTC). The recently proposed WHO-EORTC consensus classification should replace them. However, despite recent progress in this field, there are still controversies and difficulties, mainly regarding the diagnosis and classification of cutaneous B-cell lymphomas. |
| Keyword: | B-lymphocytes, Lymphoma, B-cell, Lymphoma, non-Hodgkin, Skin neoplasms, Lymphoproliferative disorders |
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