Experimental model for endometriosis. Comparative histological study between the ectopic and eutopic endometrium



Document title: Experimental model for endometriosis. Comparative histological study between the ectopic and eutopic endometrium
Journal: Acta cirurgica brasileira
Database: PERIÓDICA
System number: 000285727
ISSN: 0102-8650
Authors: 1



Institutions: 1Universidade Federal de Minas Gerais, Faculdade de Medicina, Belo Horizonte, Minas Gerais. Brasil
Year:
Season: Oct-Dic
Volumen: 12
Number: 4
Pages: 226-230
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Experimental, analítico
English abstract Thyrty-six rats werw implanted with endometrial squares (2 X 2mm) to the left parietal peritoneum and the right uterine horn was tied. The rats were mated for 20 days and then sacrificed. Topic and ectopic endometrial histological pattern were compared. There was a correlation between the histological pattern of the autografted endometrium and the eutopic endometrium im most rats, pregnant or not. This suggests that both responded in a similar way to the same endocrine stimuli. The experimental model for endometriosis admiting the histological correlation between the uterine endometrium and the ectopic is factible and it is easy to be repetead
Portuguese abstract Trinta e seis ratas foram submetidas a implante cirúrgico de retalho endometrial quadrangular (2 x 2mm) no peritônio parietal esquerdo e ligadura do corno uterino direito. As ratas foram acasaladas por 20 dias e logo após sacrificadas. Foram comparados o padrão histológico do endométrio eutópico e do ectópico.Houve correspondência entre o padrão histológico do endométrio auto-transplantado e o endométrio eutópico na maioria das ratas, prenhes ou não, sugerindo que ambos responderam de forma semelhante aos mesmo estímulos endócrinos. O modelo experimental de endometriose na rata, permitindo a correlação histológica entre o endométrio uterino e o ectópico, é viável e de fácil repetição
Disciplines: Medicina
Keyword: Cirugía,
Medicina experimental,
Anatomía e histología,
Endometriosis,
Ratas,
Endometrio
Keyword: Medicine,
Experimental medicine,
Surgery,
Endometriosis,
Rats,
Endometrium,
Anatomy and histology
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