| Revista: | Memorias do Instituto Oswaldo Cruz |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000459446 |
| ISSN: | 0074-0276 |
| Autores: | Rêgo, Felipe Dutra1 Silva, Eduardo Sérgio da2 Lopes, Valeriana Valadares2 Teixeira-Neto, Rafael Goncalves2 Belo, Vinícius Silva2 Fonseca-Junior, Antonio Augusto3 Pereira, Diego Andrade2 Pena, Heber Paulino2 Laurenti, Márcia Dalastra4 Araújo, Gabriela V4 Matta, Vânia Lúcia Ribeiro da4 Chouman, Islam Hussein4 Burrin, Thainá Bergantin4 Sandoval, Carmen M4 Barrouin Melo, Stella Maria5 Pinho, Flaviane Alves de5 Andrade, Hélida Monteiro de6 Nunes, Ramon Vieira6 Gontijo, Célia Maria Ferreira1 Soccol, Vanete Thomaz7 Klocek, Donnamae8 Grybchuk, Danyil8 Macedo, Diego Henrique8 Monte-Neto, Rubens Lima do1 Yurchenko, Vyacheslav8 Soares, Rodrigo Pedro1 |
| Instituciones: | 1Fundacao Oswaldo Cruz, Instituto Rene Rachou, Belo Horizonte, Minas Gerais. Brasil 2Universidade Federal de Sao Joao del Rei, Laboratorio de Doencas Parasitarias e Infecciosas, Divinopolis, Minas Gerais. Brasil 3Ministerio da Agricultura, Pecuaria e Abastecimento, Laboratorio Nacional Agropecuaria, Pedro Leopoldo, Minas Gerais. Brasil 4Universidade de Sao Paulo, Faculdade de Medicina, Sao Paulo. Brasil 5Universidade Federal da Bahia, Departamento de Anatomia, Patologia e Clinicas Veterinarias, Salvador, Bahia. Brasil 6Universidade Federal de Minas Gerais, Instituto de Ciencias Biologicas, Belo Horizonte, Minas Gerais. Brasil 7Universidade Federal do Parana, Departamento de Engenharia de Bioprocessos e Biotecnologia, Curitiba, Parana. Brasil 8University of Ostrava, Faculty of Science, Ostrava. República Checa |
| Año: | 2023 |
| Volumen: | 118 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Aplicado, descriptivo |
| Resumen en inglés | Leishmania RNA virus 1 (LRV1) is commonly found in South American Leishmania parasites belonging to the subgenus Viannia, whereas Leishmania RNA virus 2 (LRV2) was previously thought to be restricted to the Old-World pathogens of the subgenus Leishmania. OBJECTIVES In this study, we investigated the presence of LRV2 in strains of Leishmania (L.) infantum, the causative agent of visceral leishmaniasis (VL), originating from different hosts, clinical forms, and geographical regions. METHODS A total of seventy-one isolates were screened for LRV2 using semi-nested reverse transcription-polymerase chain reaction (RT-PCR) targeting the RNA-dependent RNA polymerase (RdRp) gene. FINDINGS We detected LRV2 in two L. infantum isolates (CUR268 and HP-EMO) from canine and human cases, respectively. MAIN CONCLUSIONS To the best of our knowledge, this is the first detection of LRV2 in the New World |
| Disciplinas: | Biología |
| Palabras clave: | Protozoarios, Virus, Leishmaniasis, Leishmania infantum, Virus de ARN, Totiviridae |
| Keyword: | Protozoa, Virus, Leishmaniasis, Leishmania infantum, RNA virus, Totiviridae |
| Texto completo: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
