Revista: | International braz j urol |
Base de datos: | PERIÓDICA |
Número de sistema: | 000296452 |
ISSN: | 1677-5538 |
Autores: | Dall'Oglio, Marcos1 Srougi, Miguel2 Barbuto, Jose A.M3 |
Instituciones: | 1Universidade Federal de Sao Paulo, Escola Paulista de Medicina, Ribeirao Preto, Sao Paulo. Brasil 2Hospital Sirio Libanes, Sao Paulo. Brasil 3Universidade de Sao Paulo, Instituto de Ciencias Biomedicas, Sao Paulo. Brasil |
Año: | 2003 |
Periodo: | Nov-Dic |
Volumen: | 29 |
Número: | 6 |
Paginación: | 517-519 |
País: | Brasil |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Enfoque: | Caso clínico, descriptivo |
Resumen en inglés | INTRODUCTION: We report a case of metastatic renal cell carcinoma that presented involution following therapy with dendritic cells. CASE REPORT: Male, 51-year old patient underwent left radical nephrectomy in September 1999 due to renal cell carcinoma, evolved with recurrence of the neoplasia in January 2002, confirmed by resection of the lesion. A vaccine therapy based on dendritic cells was then performed during 5 months (4 applications). After this period, there was occurrence of new lesions, whose resection revealed areas of necrosis and inflammatory infiltrate. DISCUSSION: The outcome of renal cell carcinoma is influenced by prognostic factors that confer more aggressive tumor characteristics. However, in cases of recurrence, the systemic therapy with dendritic cells-based vaccine can be associated with a better outcome with regression of disease |
Disciplinas: | Medicina |
Palabras clave: | Cirugía, Oncología, Neoplasias, Riñones, Carcinoma, Metástasis, Células dendríticas, Vacunas |
Keyword: | Medicine, Oncology, Surgery, Neoplasms, Kidneys, Carcinoma, Metastasis, Dendritic cells, Vaccines |
Texto completo: | Texto completo (Ver HTML) |