Complete response of metastatic renal cancer with dendritic cell vaccine



Título del documento: Complete response of metastatic renal cancer with dendritic cell vaccine
Revista: International braz j urol
Base de datos: PERIÓDICA
Número de sistema: 000296452
ISSN: 1677-5538
Autores: 1
2
3
Instituciones: 1Universidade Federal de Sao Paulo, Escola Paulista de Medicina, Ribeirao Preto, Sao Paulo. Brasil
2Hospital Sirio Libanes, Sao Paulo. Brasil
3Universidade de Sao Paulo, Instituto de Ciencias Biomedicas, Sao Paulo. Brasil
Año:
Periodo: Nov-Dic
Volumen: 29
Número: 6
Paginación: 517-519
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico, descriptivo
Resumen en inglés INTRODUCTION: We report a case of metastatic renal cell carcinoma that presented involution following therapy with dendritic cells. CASE REPORT: Male, 51-year old patient underwent left radical nephrectomy in September 1999 due to renal cell carcinoma, evolved with recurrence of the neoplasia in January 2002, confirmed by resection of the lesion. A vaccine therapy based on dendritic cells was then performed during 5 months (4 applications). After this period, there was occurrence of new lesions, whose resection revealed areas of necrosis and inflammatory infiltrate. DISCUSSION: The outcome of renal cell carcinoma is influenced by prognostic factors that confer more aggressive tumor characteristics. However, in cases of recurrence, the systemic therapy with dendritic cells-based vaccine can be associated with a better outcome with regression of disease
Disciplinas: Medicina
Palabras clave: Cirugía,
Oncología,
Neoplasias,
Riñones,
Carcinoma,
Metástasis,
Células dendríticas,
Vacunas
Keyword: Medicine,
Oncology,
Surgery,
Neoplasms,
Kidneys,
Carcinoma,
Metastasis,
Dendritic cells,
Vaccines
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