Revista: | Gaceta médica de Caracas |
Base de datos: | |
Número de sistema: | 000595944 |
ISSN: | 2739-0012 |
Autores: | Mamontov, Ivan1 Tamm, Tamara1 Ivakhno, Ihor2 Panasenko, Viacheslav3 Padalko, Volodymyr4 Nepomniashchyi, Valentyn1 Yaroshenko, Alina5 |
Instituciones: | 1Kharkiv National Medical University, Department of Surgery No. 6, Kharkiv. Ucrania 2Kharkiv National Medical University, Department of Pathological Anatomy and Forensic Medical Examination, Kharkiv. Ucrania 3Kharkiv National Medical University, Department of Histology, Cytology and Embryology, Kharkiv. Ucrania 4V.N. Karazin Kharkiv National University, Department of General and Clinical Pathology, Kharkiv. Ucrania 5Kharkiv National Medical University, Department of Therapy No. 2, Kharkiv. Ucrania |
Año: | 2023 |
Volumen: | 131 |
Número: | 4 |
País: | Venezuela |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Resumen en español | Objective: This work aimed to establish histological changes in the structure and activity of the liver caused by experimental obstructive cholestasis. Method: Several methodological approaches were used such as experimental, biochemical, and comparison were applied.Results: It was possible to describe the essence of such a disease as cholestasis and its impact on the liver. At the same time, it was proved that recanalization with incomplete recovery of bile outflow was possible due to the normalization of the total bilirubin (TB) level. Morphological changes in the liver were most pronounced during acute cholangitis. The study examined what processes occur in the body during the recovery of bile flow, including after the complete blockage of such organs as the liver and bile ducts. Consequently, signs that expressed the abnormality of the liver structure of animals were revealed. |
Disciplinas: | Medicina |
Palabras clave: | Gastroenterología |
Keyword: | Gastroenterology |
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