Histological Liver Changes in Experimental Obstructive Cholestasis with Partial Outflow Restoration



Título del documento: Histological Liver Changes in Experimental Obstructive Cholestasis with Partial Outflow Restoration
Revista: Gaceta médica de Caracas
Base de datos:
Número de sistema: 000595944
ISSN: 2739-0012
Autores: 1
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Instituciones: 1Kharkiv National Medical University, Department of Surgery No. 6, Kharkiv. Ucrania
2Kharkiv National Medical University, Department of Pathological Anatomy and Forensic Medical Examination, Kharkiv. Ucrania
3Kharkiv National Medical University, Department of Histology, Cytology and Embryology, Kharkiv. Ucrania
4V.N. Karazin Kharkiv National University, Department of General and Clinical Pathology, Kharkiv. Ucrania
5Kharkiv National Medical University, Department of Therapy No. 2, Kharkiv. Ucrania
Año:
Volumen: 131
Número: 4
País: Venezuela
Idioma: Inglés
Tipo de documento: Artículo
Resumen en español Objective: This work aimed to establish histological changes in the structure and activity of the liver caused by experimental obstructive cholestasis. Method: Several methodological approaches were used such as experimental, biochemical, and comparison were applied.Results: It was possible to describe the essence of such a disease as cholestasis and its impact on the liver. At the same time, it was proved that recanalization with incomplete recovery of bile outflow was possible due to the normalization of the total bilirubin (TB) level. Morphological changes in the liver were most pronounced during acute cholangitis. The study examined what processes occur in the body during the recovery of bile flow, including after the complete blockage of such organs as the liver and bile ducts. Consequently, signs that expressed the abnormality of the liver structure of animals were revealed.
Disciplinas: Medicina
Palabras clave: Gastroenterología
Keyword: Gastroenterology
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