| Revista: | Gaceta médica de Caracas |
| Base de datos: | |
| Número de sistema: | 000595944 |
| ISSN: | 2739-0012 |
| Autores: | Mamontov, Ivan1 Tamm, Tamara2 Ivakhno, Ihor3 Panasenko, Viacheslav4 Padalko, Volodymyr5 Nepomniashchyi, Valentyn1 Yaroshenko, Alina6 |
| Instituciones: | 1Department of Surgery No. 6, Kharkiv National Medical University, Ukraine, Kharkiv 61022, 2Department of Surgery No. 6, Kharkiv National Medical University, Ukraine, Kharkiv 61022, 3Department of Pathological Anatomy and Forensic Medical Examination, Kharkiv National Medical University, Ukraine, Kharkiv 61022, 4Department of Histology, Cytology and Embryology, Kharkiv National Medical University, Ukraine, Kharkiv 61022, 5Department of General and Clinical Pathology, V.N. Karazin Kharkiv National University, Ukraine, Kharkiv 61022, 6Department of Therapy No. 2, Kharkiv National Medical University, Ukraine, Kharkiv 61022, |
| Año: | 2023 |
| Volumen: | 131 |
| Número: | 4 |
| País: | Venezuela |
| Idioma: | Español |
| Resumen en español | Objective: This work aimed to establish histological changes in the structure and activity of the liver caused by experimental obstructive cholestasis. Method: Several methodological approaches were used such as experimental, biochemical, and comparison were applied.Results: It was possible to describe the essence of such a disease as cholestasis and its impact on the liver. At the same time, it was proved that recanalization with incomplete recovery of bile outflow was possible due to the normalization of the total bilirubin (TB) level. Morphological changes in the liver were most pronounced during acute cholangitis. The study examined what processes occur in the body during the recovery of bile flow, including after the complete blockage of such organs as the liver and bile ducts. Consequently, signs that expressed the abnormality of the liver structure of animals were revealed. |
| Palabras clave: | Complete obstruction, TB level, bile ducts, recanalization, fibrosis |
| Texto completo: | Texto completo (Ver PDF) Texto completo (Ver HTML) |
