Revista: | Annals of hepatology |
Base de datos: | PERIÓDICA |
Número de sistema: | 000412991 |
ISSN: | 1665-2681 |
Autores: | Ju Dong Yang1 Girotra, Mohit1 Restrepo, Alejandro1 Waheed, Sarah1 Barlogie, Bart1 Duarte Rojo, Andrés1 |
Instituciones: | 1University of Arkansas for Medical Sciences, Myeloma Institute for Research and Therapy, Little Rock, Arkansas. Estados Unidos de América |
Año: | 2014 |
Periodo: | Jul-Ago |
Volumen: | 13 |
Número: | 4 |
Paginación: | 461-465 |
País: | México |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Enfoque: | Caso clínico, analítico |
Resumen en inglés | Hepatitis B virus (HBV) reactivation is a well-established complication of severe immunosuppression in patients with hematologic malignancy and positive hepatitis B surface antigen (HBsAg). Patients who receive high-dose chemotherapy, corticosteroids, rituximab, or have a bone marrow transplant are particularly at increased risk for HBV reactivation. However, limited information is available in the literature regarding HBV reactivation in patients with isolated anti-HBc, particularly in the setting of multiple myeloma (MM). We report two cases of HBV reactivation in MM patients with isolated anti-HBc positive with a rather atypical presentation. In conclusion, our cases highlight that clinicians need to be cognizant about this potentially fatal but preventable complication of chemotherapy and immunosuppression |
Disciplinas: | Medicina |
Palabras clave: | Gastroenterología, Oncología, Inmunología, Hepatitis viral, Quimioterapia, Hepatitis B, Reactivación, Médula ósea, Trasplantes, Mieloma múltiple |
Keyword: | Medicine, Gastroenterology, Oncology, Immunology, Viral hepatitis, Chemotherapy, Hepatitis B, Reactivation, Bone marrow, Transplantation, Multiple myeloma |
Texto completo: | Texto completo (Ver PDF) |