Hepatitis B reactivation in patients with multiple myeloma and isolated positive hepatitis B core antibody: a call for greater cognizance
Título del documento: Hepatitis B reactivation in patients with multiple myeloma and isolated positive hepatitis B core antibody: a call for greater cognizance
Revista: Annals of hepatology
Base de datos: PERIÓDICA
Número de sistema: 000412991
ISSN: 1665-2681
Autors: 1
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Institucions: 1University of Arkansas for Medical Sciences, Myeloma Institute for Research and Therapy, Little Rock, Arkansas. Estados Unidos de América
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Període: Jul-Ago
Volum: 13
Número: 4
Paginació: 461-465
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico, analítico
Resumen en inglés Hepatitis B virus (HBV) reactivation is a well-established complication of severe immunosuppression in patients with hematologic malignancy and positive hepatitis B surface antigen (HBsAg). Patients who receive high-dose chemotherapy, corticosteroids, rituximab, or have a bone marrow transplant are particularly at increased risk for HBV reactivation. However, limited information is available in the literature regarding HBV reactivation in patients with isolated anti-HBc, particularly in the setting of multiple myeloma (MM). We report two cases of HBV reactivation in MM patients with isolated anti-HBc positive with a rather atypical presentation. In conclusion, our cases highlight that clinicians need to be cognizant about this potentially fatal but preventable complication of chemotherapy and immunosuppression
Disciplines Medicina
Paraules clau: Gastroenterología,
Oncología,
Inmunología,
Hepatitis viral,
Quimioterapia,
Hepatitis B,
Reactivación,
Médula ósea,
Trasplantes,
Mieloma múltiple
Keyword: Medicine,
Gastroenterology,
Oncology,
Immunology,
Viral hepatitis,
Chemotherapy,
Hepatitis B,
Reactivation,
Bone marrow,
Transplantation,
Multiple myeloma
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