An in vivo method for estimating the concentration of crotamine in a solution



Título del documento: An in vivo method for estimating the concentration of crotamine in a solution
Revista: The journal of venomous animals and toxins
Base de datos: PERIÓDICA
Número de sistema: 000298586
ISSN: 0104-7930
Autores: 1
Instituciones: 1Universidade Federal do Rio Grande do Sul, Instituto de Biociencias, Porto Alegre, Rio Grande do Sul. Brasil
Año:
Volumen: 3
Número: 1
Paginación: 33-36
País: Brasil
Idioma: Inglés
Tipo de documento: Nota breve o noticia
Enfoque: Experimental
Resumen en inglés very sensitive method for estimating the concentration of crotamine in a solution was developed. This method was based on the time required for the appearance of permanent hyperextension of the rear legs of mice as a function of the dose administered. This method can be used to determine toxin doses as low as 0.32 mg/kg. Its high specificity for crotamine means that it can be used to measure toxin concentrations in the presence of other proteins and polypeptides
Disciplinas: Biología
Palabras clave: Bioquímica,
Reptiles,
Veneno de víbora,
Crotamina,
Concentración,
Métodos analíticos,
Crotalus durissus terrificus
Keyword: Biology,
Biochemistry,
Reptiles,
Snake venom,
Crotamine,
Concentration,
Analytical methods,
Crotalus durissus terrificus
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