Predictive Value of Uric Acid/Albumin Ratio for the Prediction of New-Onset Atrial Fibrillation in Patients with ST-Elevation Myocardial Infarction



Título del documento: Predictive Value of Uric Acid/Albumin Ratio for the Prediction of New-Onset Atrial Fibrillation in Patients with ST-Elevation Myocardial Infarction
Revista: Revista de investigación clínica
Base de datos: PERIÓDICA
Número de sistema: 000452960
ISSN: 0034-8376
Autores: 1
1
2
2
1
1
3
4
Instituciones: 1Abdülhamid Han Training and Research Hospital, Estambul. Turquía
2Van Training and Research Hospital, Van. Turquía
3Dr. Siyami Ersek Training and Research Hospital, Estambul. Turquía
4Nisantasi University, School of Health Science, Estambul. Turquía
Año:
Periodo: May-Jun
Volumen: 74
Número: 3
Paginación: 156-164
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Aplicado, descriptivo
Resumen en inglés Background: There is a lack of studies supporting the association between the uric acid/albumin ratio (UAR) and the development of new-onset atrial fibrillation (NOAF) in ST-elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (pPCI). Objective: The objective of the study was to assess the efficacy of the UAR for predicting the occurrence of NOAF in STEMI patients undergoing pPCI. Methods: We recruited 1484 consecutive STEMI patients in this retrospective and cross-sectional investigation. The population sample was classified based on the development of NOAF during hospitalization. NOAF was defined as an atrial fibrillation (AF) observed during hospitalization in patients without a history of AF or atrial flutter. The UAR was computed by dividing the serum uric acid (UA) level by serum albumin level. Results: After pPCI, 119 STEMI patients (8%) were diagnosed with NOAF. NOAF patients had higher serum UAR levels than individuals who did not have NOAF. According to the multivariable logistic regression model, the UAR was an independent predictor for NOAF in STEMI patients (OR: 6.951, 95% CI: 2.978-16.28, p < 0.001). The area under curve (AUC) value of the UAR in a receiver operating characteristics (ROC) evaluation was 0.758, which was greater than those of its components (albumin [AUC: 0.633] and UA [AUC: 0.647]) and C-reactive protein (AUC: 0.714). The optimal UAR value in predicting NOAF in STEMI patients was greater than 1.39, with a sensitivity of 69% and a specificity of 74.5%. Conclusion: To the best of our knowledge, this is the first study indicating that the UAR was an independent predictor of NOAF development in STEMI patients
Disciplinas: Medicina
Palabras clave: Sistema cardiovascular,
Diagnóstico,
Relación ácido úrico-albúmina,
Infarto al miocardio,
Fibrilación atrial
Keyword: Cardiovascular system,
Diagnosis,
Uric acid-albumin ratio,
Atrial fibrillation,
Myocardial infarction
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