| Revista: | Revista de investigación clínica |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000452960 |
| ISSN: | 0034-8376 |
| Autors: | Selçuk, Murat1 Çinar, Tufan1 Şaylik, Faysal2 Akbulut, Tayyar2 Asal, Suha1 Çiçek, Vedat1 Hayiroğlu, Mert İlker3 Tanboğa, İbrahim Halil4 |
| Institucions: | 1Abdülhamid Han Training and Research Hospital, Estambul. Turquía 2Van Training and Research Hospital, Van. Turquía 3Dr. Siyami Ersek Training and Research Hospital, Estambul. Turquía 4Nisantasi University, School of Health Science, Estambul. Turquía |
| Any: | 2022 |
| Període: | May-Jun |
| Volum: | 74 |
| Número: | 3 |
| Paginació: | 156-164 |
| País: | México |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Aplicado, descriptivo |
| Resumen en inglés | Background: There is a lack of studies supporting the association between the uric acid/albumin ratio (UAR) and the development of new-onset atrial fibrillation (NOAF) in ST-elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (pPCI). Objective: The objective of the study was to assess the efficacy of the UAR for predicting the occurrence of NOAF in STEMI patients undergoing pPCI. Methods: We recruited 1484 consecutive STEMI patients in this retrospective and cross-sectional investigation. The population sample was classified based on the development of NOAF during hospitalization. NOAF was defined as an atrial fibrillation (AF) observed during hospitalization in patients without a history of AF or atrial flutter. The UAR was computed by dividing the serum uric acid (UA) level by serum albumin level. Results: After pPCI, 119 STEMI patients (8%) were diagnosed with NOAF. NOAF patients had higher serum UAR levels than individuals who did not have NOAF. According to the multivariable logistic regression model, the UAR was an independent predictor for NOAF in STEMI patients (OR: 6.951, 95% CI: 2.978-16.28, p < 0.001). The area under curve (AUC) value of the UAR in a receiver operating characteristics (ROC) evaluation was 0.758, which was greater than those of its components (albumin [AUC: 0.633] and UA [AUC: 0.647]) and C-reactive protein (AUC: 0.714). The optimal UAR value in predicting NOAF in STEMI patients was greater than 1.39, with a sensitivity of 69% and a specificity of 74.5%. Conclusion: To the best of our knowledge, this is the first study indicating that the UAR was an independent predictor of NOAF development in STEMI patients |
| Disciplines | Medicina |
| Paraules clau: | Sistema cardiovascular, Diagnóstico, Relación ácido úrico-albúmina, Infarto al miocardio, Fibrilación atrial |
| Keyword: | Cardiovascular system, Diagnosis, Uric acid-albumin ratio, Atrial fibrillation, Myocardial infarction |
| Text complet: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
