Revista: | Revista de investigación clínica |
Base de datos: | PERIÓDICA |
Número de sistema: | 000390742 |
ISSN: | 0034-8376 |
Autores: | González Ramírez, Mónica P1 Miravete Lagunes, Karla2 Gómez de León, Andrés3 Ponce de León, Sergio4 Tenorio Rojo, Andrea P1 Martagón Herrera, Nora A1 Hernández Reyes, Jesús A1 García Villasenor, Arturo2 Burguette, Esteban2 Vallejo Villalobos, María Fernanda5 Ruiz Delgado, Guillermo J1 Gómez Almaguer, David3 Ruiz Argüelles, Guillermo J1 |
Instituciones: | 1Clínica Ruiz de Puebla, Centro de Hematología y Medicina Interna, Puebla. México 2Universidad de las Américas, Puebla. México 3Universidad Autónoma de Nuevo León, Hospital Universitario Dr. José Eleuterio González, Monterrey, Nuevo León. México 4Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, Distrito Federal. México 5Universidad Popular Autónoma del Estado de Puebla, Puebla. México |
Año: | 2015 |
Periodo: | Mar-Abr |
Volumen: | 67 |
Número: | 2 |
Paginación: | 109-116 |
País: | México |
Idioma: | Inglés |
Tipo de documento: | Estadística o encuesta |
Enfoque: | Analítico |
Resumen en inglés | Quality of life (QOL) is an important consideration in the counseling, implementation, and post-treatment management of arduous treatments for life-threatening conditions such as allogeneic hematopoietic cell transplantation (allo-HCT). Objective: To analyze the QOL of leukemia patients allografted with the Mexican reduced-intensity conditioning regimen in two Mexican academic medical centers. Material and methods: By means of the quality metric short form 36 version 2 to measure generic health concepts, relevant QOL was analyzed in leukemia patients who underwent allo-HCT using reducedintensity conditioning on an outpatient basis at either the Centro de Hematología y Medicina Interna de Puebla of the Clínica Ruiz or the Hematology Service of the Internal Medicine Department of the Hospital “Dr. José Eleuterio González” of the Universidad Autónoma de Nuevo León, and who had survived more than 12 months after the allograft, who could be approached, who were in a continued complete remission (with or without graft-versus-host disease), and who were willing to respond to the questionnaire. Thirty-five patients fulfilling these requirements were included, and a sex- and age-matched group of 35 reference subjects was also studied. Results: Allografted patients were found to have a slightly better mental component summary than the reference subjects (53.23 vs. 48.66 points; p = 0.01), whereas the physical component summary did not show a difference (54.53 vs. 52.05 points; p = 0.59). Most of the differences between allografted individuals and reference subject controls were not significant. Conclusions: Despite several sources of bias, these data suggest that allografted individuals employing the Mexican reduced-intensity conditioning regimen enjoy a health-related QOL life similar to that of reference subjects, adding another advantage of this method of conducting stem cell allografts. However |
Disciplinas: | Medicina |
Palabras clave: | Oncología, Salud pública, Calidad de vida, Salud, Trasplantes, Células madre hematopoyéticas, Leucemia, Aloinjertos |
Keyword: | Medicine, Oncology, Public health, Quality of life, Health, Transplantation, Hematopoietic stem cells, Leukemia, Allografts |
Texto completo: | Texto completo (Ver PDF) |