La arquitectura nuclear y su dinámica



Título del documento: La arquitectura nuclear y su dinámica
Revista: REB. Revista de educación bioquímica
Base de datos: PERIÓDICA
Número de sistema: 000369265
ISSN: 1665-1995
Autores: 1
2
Instituciones: 1Universidad Nacional Autónoma de México, Instituto de Fisiología Celular, México, Distrito Federal. México
Año:
Volumen: 27
Número: 4
Paginación: 130-137
País: México
Idioma: Español
Tipo de documento: Artículo
Enfoque: Descriptivo
Resumen en inglés Cell nucleus represents the natural environment for the eukaryotic genome. The progress on fluorescent reagents for molecular labeling and fluorescence microscopy revealed the nucleus and the genome spatial compartmentalization demonstrating that the cell nucleus is much more complex than previously anticipated. It is well established that transcription and splicing are nuclear processes but today the nucleus needs to be seen as a more dynamic organelle where chromosomes are confined to specific territories and with dynamic re-localization of chromatin fibers inducing inter-chromosomal and intra-chromosomal interactions. This modern view of the eukaryotic cell nucleus illustrates its contribution at multiple levels to genetic and epigenetic regulation
Disciplinas: Biología
Palabras clave: Biología celular,
Fisiología celular,
Núcleo,
Cromatina,
ADN
Keyword: Biology,
Cell biology,
Cell physiology,
Nucleus,
Chromatin,
DNA
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