Testicular mixed germ cell tumor presenting with seizure as the initial symptom: a case report and literature review



Título del documento: Testicular mixed germ cell tumor presenting with seizure as the initial symptom: a case report and literature review
Revista: International braz j urol
Base de datos: PERIÓDICA
Número de sistema: 000434775
ISSN: 1677-5538
Autors: 1
1
1
Institucions: 1Taipei Medical University, Wan Fang Hospital, Taipei. Taiwán
2Taipei Medical University, College of Medicine, Taipei City. Taiwán
Any:
Període: May-Jun
Volum: 45
Número: 3
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico, descriptivo
Resumen en inglés Most patients with testicular germ cell tumor present with a painless scrotal mass. We report a 19-year-old patient who presented with neurological complains. Rapid clinical progression to coma was noted during the staging work up. A diagnosis of testicular mixed germ cell tumor with multiorgan metastasis (lymph node, lung, liver and brain) was made. Patients with brain metastasis should receive chemotherapy alone or combined with surgery or radiotherapy. Because the clinical symptoms deteriorated quickly, surgery was used upfront followed by chemotherapy and radiotherapy for the brain tumor. After the first stage of treatment, the clinical symptoms, tumor markers and imaging findings were improved. The residual brain tumor was eliminated by chemotherapy, and only sparse degenerated tumor cells were noted in the brain tissue. Longer follow up is required to assess the impact of our treatment strategy
Disciplines Medicina
Paraules clau: Urología,
Oncología,
Tumor testicular de células germinales,
Metástasis,
Cerebro
Keyword: Urology,
Oncology,
Testicular germ cells tumor,
Metastasis,
Brain
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