| Journal: | Memorias do Instituto Oswaldo Cruz |
| Database: | PERIÓDICA |
| System number: | 000405560 |
| ISSN: | 0074-0276 |
| Authors: | Goncalves-Macedo, Liana1 Lopes, Edmundo Pessoa2 Domingues, Ana Lucia Coutinho2 Markman-Filho, Brivaldo2 Mota, Vitor Gomes2 Luna, Carlos Feitosa3 |
| Institutions: | 1Universidade Federal de Pernambuco, Programa de Pos-Graduacao em Medicina Tropical, Recife, Pernambuco. Brasil 2Universidade Federal de Pernambuco, Departamento de Medicina Clinica, Recife, Pernambuco. Brasil 3Fundacao Oswaldo Cruz, Laboratorio de Metodos Quantitativos em Saude, Recife, Pernambuco. Brasil |
| Year: | 2017 |
| Season: | Jul |
| Volumen: | 112 |
| Number: | 7 |
| Pages: | 469-473 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | Hepatopulmonary syndrome (HPS) is defined as an oxygenation defect induced by intrapulmonary vasodilation in patients with liver disease or portal hypertension. It is investigated in patients with liver cirrhosis and less frequently in those with portal hypertension without liver cirrhosis, as may occur in hepatosplenic schistosomiasis (HSS). OBJECTIVES To investigate the prevalence of HPS in patients with HSS, and to determine whether the occurrence of HPS is influenced by concomitant cirrhosis. METHODS We evaluated patients with HSS with or without concomitant liver cirrhosis. All patients underwent laboratory testing, ultrasound, endoscopy, contrast echocardiography, and arterial blood gas analysis. FINDINGS Of the 121 patients with HSS, 64 were also diagnosed with liver cirrhosis. HPS was diagnosed in 42 patients (35%) and was more frequent among patients with concomitant liver cirrhosis than in those without cirrhosis (42% vs. 26%), but the difference was not significant (p = 0.069). HPS was more common in those with spider naevi, Child-Pugh classes B or C and high model for end stage liver disease (MELD) scores (p < 0.05 each). MAIN CONCLUSIONS The prevalence of HPS was 35% in this study. The occurrence of liver cirrhosis concomitantly with HSS may have influenced the frequency of patients presenting with HPS |
| Disciplines: | Medicina |
| Keyword: | Gastroenterología, Parasitología, Esquistosomiasis, Síndrome hepatopulmonar, Várices esofágicas, Várices gástricas, Hipertensión portal |
| Keyword: | Medicine, Gastroenterology, Parasitology, Schistosomiasis, Hepatopulmonary syndrome, Esophageal varices, Gastric varices, Portal hypertension |
| Full text: | Texto completo (Ver HTML) |
