| Journal: | Genetics and molecular biology |
| Database: | PERIÓDICA |
| System number: | 000401314 |
| ISSN: | 1415-4757 |
| Authors: | Reis, Evelyze Pinheiro dos1 Paixao, Debora Martins1 Brustolini, Otavio Jose Bernardes2 Silva, Fabyano Fonseca e1 Silva, Walmir1 Araujo, Flavio Marcos Gomes de3 Salim, Anna Christina de Matos3 Oliveira, Guilherme4 Guimaraes, Simone Eliza Facioni1 |
| Institutions: | 1Universidade Federal de Vicosa, Departamento de Zootecnia, Vicosa, Minas Gerais. Brasil 2Universidade Federal de Vicosa, Departamento de Bioquimica Agricola, Vicosa, Minas Gerais. Brasil 3Fundacao Instituto Oswaldo Cruz, Centro de Pesquisas Rene Rachou, Belo Horizonte, Minas Gerais. Brasil 4Instituto Tecnologico Vale, Belem, Para. Brasil |
| Year: | 2016 |
| Season: | Dic |
| Volumen: | 39 |
| Number: | 4 |
| Pages: | 589-599 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | This study used qRT-PCR to examine variation in the expression of 13 myogenes during muscle development in four prenatal periods (21, 40, 70 and 90 days post-insemination) in commercial (the three-way Duroc, Landrace and Large-White cross) and local Piau pig breeds that differ in muscle mass. There was no variation in the expression of the CHD8, EID2B, HIF1AN, IKBKB, RSPO3, SOX7 and SUFU genes at the various prenatal ages or between breeds. The MAP2K1 and RBM24 genes showed similar expression between commercial and Piau pigs but greater expression (p < 0.05) in at least one prenatal period. Pair-wise comparisons of prenatal periods in each breed showed that only the CSRP3, LEF1, MRAS and MYOG genes had higher expression (p < 0.05) in at least one prenatal period in commercial and Piau pigs. Overall, these results identified the LEF1 gene as a primary candidate to account for differences in muscle mass between the pig breeds since activation of this gene may lead to greater myoblast fusion in the commercial breed compared to Piau pigs. Such fusion could explain the different muscularity between breeds in the postnatal periods |
| Disciplines: | Medicina veterinaria y zootecnia |
| Keyword: | Porcinos, Reproducción y genética animal, Miogénesis, Expresión génica, Cerdos |
| Keyword: | Veterinary medicine and animal husbandry, Animal reproduction and genetics, Swine, Myogenesis, Gene expression, Pigs |
| Full text: | Texto completo (Ver HTML) |
