Polycystic ovarian syndrome: temporal characterization of the induction and reversion process in an experimental model



Document title: Polycystic ovarian syndrome: temporal characterization of the induction and reversion process in an experimental model
Journal: Brazilian journal of veterinary research and animal science
Database: PERIÓDICA
System number: 000291816
ISSN: 1413-9596
Authors: 1

2
Institutions: 1Universidad Nacional del Litoral, Facultad de Ciencias Veterinarias, Santa Fe. Argentina
2Universidad Nacional de La Plata, Instituto de Patología, La Plata, Buenos Aires. Argentina
Year:
Season: Nov-Dic
Volumen: 41
Number: 6
Pages: 389-395
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Experimental
English abstract Numerous experimental models have been developed for the study of the polycystic ovarian syndrome in the rat. In the present study, the syndrome was induced by exposure to constant light. The process was evaluated during its induction and also during its reversion. The estral cycle was analyzed through the vaginal cytology; reproductive parameters were evaluated by mating, as well as the ovarian morphology. All the animals developed the syndrome after 13 weeks of permanent light. The histologic characteristics of the ovaries, at week 15, were similar to those observed in the polycystic ovarian syndrome in human and other species. After regression of the syndrome, there was not difference in any of the evaluated reproductive parameters, when compared with the control group
Portuguese abstract Numerosos modelos experimentais têm sido desenvolvimos para o estudo da síndrome do ovário policístico em ratos. No presente estudo, a síndrome foi inducida por exposição à luz constante. O processo foi avaliado durante sua indução e inclusive durante sua reversão. O ciclo estral foi analisado através de citologia vaginal; parámetros reprodutivos foram avaliados por acasalamento, bem como a morfologia ovariana. Todos animais desenvolveram a síndrome depois de 13 semanas de luz permanente. As características histológicas dos ovários, na semana 15, foram similares àquelas observadas na síndrome do ovário policístico em humanos e outras espécies. Após a regressão da síndrome, não houve diferenta em nenhum dos parámetros reprodutivos avaliados, quando comparados com o grupo controle
Disciplines: Biología
Keyword: Anatomía e histología,
Mamíferos,
Reproducción y desarrollo,
Histopatología,
Ovarios,
PCOD,
Síndrome de ovarios poliquísticos
Keyword: Biology,
Anatomy and histology,
Mammals,
Reproduction and development,
Histopathology,
Ovaries,
Polycystic ovary syndrome,
Rats
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